64490-92-2|Sodium tolmetin dihydrateProducts Supply

Sodium tolmetin dihydrate cas no:64490-92-2

Synonyms: 1H-Pyrrole-2-aceticacid, 1-methyl-5-(4-methylbenzoyl)-, sodium salt, dihydrate (9CI);1H-Pyrrole-2-aceticacid, 1-methyl-5-(4-methylbenzoyl)-, sodium salt, hydrate (1:1:2);Tolmetin sodium;Tolumetin sodium dihydrate;

Identification

NameSodium tolmetin dihydrate
CAS64490-92-2
Synonyms1H-Pyrrole-2-aceticacid, 1-methyl-5-(4-methylbenzoyl)-, sodium salt, dihydrate (9CI);1H-Pyrrole-2-aceticacid, 1-methyl-5-(4-methylbenzoyl)-, sodium salt, hydrate (1:1:2);Tolmetin sodium;Tolumetin sodium dihydrate;
Molecular FormulaC₁₅H₁₈NNaO₅
Molecular Weight315.33

Chemical Properties

Appearancecrystalline solid
storage temp-20°C Freezer

Safety Data

Hazard Xn: Harmful;
Risk R22;R38
Safety

Moderately toxic by ingestion, intraperitoneal, and subcutaneous routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NO_x and Na₂O. See also SODIUM TOLMETIN.
Hazard Codes: Harmful Xn
Risk Statements: 22-38
R22:Harmful if swallowed.
R38:Irritating to skin.
Safety Statements: 36
S36:Wear suitable protective clothing.
WGK Germany: 3
RTECS: UX9280000

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	550mg/kg (550mg/kg)		European Patent Application. Vol. #134763,
mouse	LD50	intravenous	> 622mg/kg (622mg/kg)	GASTROINTESTINAL: ULCERATION OR BLEEDING FROM LARGE INTESTINE BLOOD: CHANGES IN SPLEEN	Kiso to Rinsho. Clinical Report. Vol. 11, Pg. 1099, 1977.
mouse	LD50	oral	899mg/kg (899mg/kg)		European Patent Application. Vol. #134763,
mouse	LD50	subcutaneous	670mg/kg (670mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH	Kiso to Rinsho. Clinical Report. Vol. 11, Pg. 1099, 1977.
rat	LD50	intraperitoneal	612mg/kg (612mg/kg)		European Patent Application. Vol. #134763,
rat	LD50	intravenous	> 724mg/kg (724mg/kg)	GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH BLOOD: CHANGES IN SPLEEN	Kiso to Rinsho. Clinical Report. Vol. 11, Pg. 1099, 1977.
rat	LD50	oral	914mg/kg (914mg/kg)		European Patent Application. Vol. #134763,
rat	LD50	subcutaneous	1050mg/kg (1050mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Kiso to Rinsho. Clinical Report. Vol. 11, Pg. 1099, 1977.

supplier list

Tianjin Harmony Technology Development Co., Ltd.: Tel:; Address: Room 601 of BokeBuilding, 100 Fukang Road, Tianjin, China

Shanghai Longschem Co.,Ltd: Tel:; Address: Shanghai Jincheng Road 338 6# 1002 Room

Hangzhou Haichem Co., Ltd.: Tel:+86-571-86025531 86024803; Address: 1218-24, Guangyin Mansion, 42 Fengqi East Road,Hangzhou, China

Fine Chem Trading LTD: Tel:+44-079-7062-7591; Address: PO Box 292, Greenford, UB6 9ZL, England

N-Techem International Co.Ltd.: Tel:; Address: Room 803, B Building, LiYuanShangDu, 39#, 158 Lane, HuanCheng XiLu, Ningbo, Zhejiang, China

Melone Pharmaceutical Co., Ltd.: Tel:; Address: Room 2209锛孨o.232, Jinma Road, Development Zone, Dalian, China

Euticals S.p.A.: Tel:; Address:

Flarer SA: Tel:+41.91.9123181; Address: Via Carona, 66900 Lugano- Paradiso

HBCChem, Inc.: Tel:+1-510-219-6317; Address:

Tianjin Harmony Technology & Development Co., Ltd.: Tel:+86-(22)-23697098; Address: Xiqing Industrial Park,Economic Development Zone, Tianjin,

Simagchem Corp.: Tel:0086-592-2680277; Address: 21F Hulong Office Bldg,No.6 Hubin East Road

Anhui Qingyun Pharmaceutical and Chemical Co., Ltd.: Tel:; Address:

LKT Laboratories, Inc.: Tel:+1-(651)-644-8357; Address: 2233 University Avenue West, St. Paul, Minnesota 55114-1629,

Tianjin harmony technology development Co.,Ltd.: Tel:+86-22-23697098; Address: Boke Building,No.100 Fukang Road,Nankai District,Tianjin,China

Watson International Trading Co.,Ltd.: Tel:+86-512-55117610; Address: Room 1209, Asia Pacific Plaza, Huaqiao International Business Park

Sodium tolmetin dihydrate cas no:64490-92-2

Directory

supplier list