64490-92-2|Sodium tolmetin dihydrateProducts Supply

Sodium tolmetin dihydrate cas no:64490-92-2

Synonyms: 1H-Pyrrole-2-aceticacid, 1-methyl-5-(4-methylbenzoyl)-, sodium salt, dihydrate (9CI);1H-Pyrrole-2-aceticacid, 1-methyl-5-(4-methylbenzoyl)-, sodium salt, hydrate (1:1:2);Tolmetin sodium;Tolumetin sodium dihydrate;

Identification

NameSodium tolmetin dihydrate
CAS64490-92-2
Synonyms1H-Pyrrole-2-aceticacid, 1-methyl-5-(4-methylbenzoyl)-, sodium salt, dihydrate (9CI);1H-Pyrrole-2-aceticacid, 1-methyl-5-(4-methylbenzoyl)-, sodium salt, hydrate (1:1:2);Tolmetin sodium;Tolumetin sodium dihydrate;
Molecular FormulaC₁₅H₁₈NNaO₅
Molecular Weight315.33

Chemical Properties

Appearancecrystalline solid
storage temp-20°C Freezer

Safety Data

Hazard Xn: Harmful;
Risk R22;R38
Safety

Moderately toxic by ingestion, intraperitoneal, and subcutaneous routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NO_x and Na₂O. See also SODIUM TOLMETIN.
Hazard Codes: Harmful Xn
Risk Statements: 22-38
R22:Harmful if swallowed.
R38:Irritating to skin.
Safety Statements: 36
S36:Wear suitable protective clothing.
WGK Germany: 3
RTECS: UX9280000

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	550mg/kg (550mg/kg)		European Patent Application. Vol. #134763,
mouse	LD50	intravenous	> 622mg/kg (622mg/kg)	GASTROINTESTINAL: ULCERATION OR BLEEDING FROM LARGE INTESTINE BLOOD: CHANGES IN SPLEEN	Kiso to Rinsho. Clinical Report. Vol. 11, Pg. 1099, 1977.
mouse	LD50	oral	899mg/kg (899mg/kg)		European Patent Application. Vol. #134763,
mouse	LD50	subcutaneous	670mg/kg (670mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH	Kiso to Rinsho. Clinical Report. Vol. 11, Pg. 1099, 1977.
rat	LD50	intraperitoneal	612mg/kg (612mg/kg)		European Patent Application. Vol. #134763,
rat	LD50	intravenous	> 724mg/kg (724mg/kg)	GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH BLOOD: CHANGES IN SPLEEN	Kiso to Rinsho. Clinical Report. Vol. 11, Pg. 1099, 1977.
rat	LD50	oral	914mg/kg (914mg/kg)		European Patent Application. Vol. #134763,
rat	LD50	subcutaneous	1050mg/kg (1050mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Kiso to Rinsho. Clinical Report. Vol. 11, Pg. 1099, 1977.

supplier list

HBCChem, Inc.: Tel:+1-510-219-6317; Address:

Tianjin Harmony Technology & Development Co., Ltd.: Tel:+86-(22)-23697098; Address: Xiqing Industrial Park,Economic Development Zone, Tianjin,

Tianjin harmony technology development Co.,Ltd.: Tel:+86-22-23697098; Address: Boke Building,No.100 Fukang Road,Nankai District,Tianjin,China

Shanghai Hope Chem Co., Ltd.: Tel:86-21-61723543; Address: Room508, Building1, No.88 CaiLun Road Zhangjiang H

Hangzhou Dayangchem Co., Ltd.: Tel:86-571-88938639; Address: 9/F Unit 2 ChangdiTorch Building, 259 #WenSan Road

Hangzhou J&H Chemical Co., Ltd: Tel:86-571-87396430; Address: No.200 Zhenhua Rd.Xihu Industrial Park, Hangzhou 310030, China

Wu han Konberd Biotech Co., Ltd.: Tel:86-27-87205925; Address: NO.666, Gaoxin Road, Eastlake High-tech zone

HEBEI CUI FENG IMPORT&EXPORT TRADE CO.,LTD: Tel:86-311-80955068; Address: No 98 Gongnong Street,Shijiazhuang Hebei,China

Zhejiang Kaili Industrial Co., Ltd.: Tel:86-571-85241926; Address: Block C&D,12/F,Lantian Business Center,No.18 Moganshan Road,Hangzhou,China

run-biotech Co., Ltd.: Tel:86-21-61900721; Address: Room 3-201, No.787, Kangqiao Road, Pudong New District, Shanghai, China

Jinan Haohua Industry Co., Ltd.: Tel:0086-531-58773055; Address: No.59 Gongye South RD

Capot Chemical Co., Ltd.: Tel:86-571-85586718; Address: Joinhands Science Park, No.4028,Nanhuan Road,

AOPHARM: Tel:86-311-66600578; Address: C-2103 Wonder Business Square, 15 Yuhua West Rd.

Wujiang Yingchuang Chemical Co., Ltd.: Tel:+86-(25)-8645 8768; Address: 215 Ying Tian Da Street, JianYe, Nanjing, Jiangsu 210017,

Watson International Trading Co.,Ltd.: Tel:+86-512-55117610; Address: Room 1209, Asia Pacific Plaza, Huaqiao International Business Park

Sodium tolmetin dihydrate cas no:64490-92-2

Directory

supplier list