L-Phenylalaninamide,L-tyrosyl-D-alanylglycyl-N-[(1S)-1-(hydroxymethyl)-3-(methylsulfinyl)propyl]-Na-methyl- cas no:64854-64-4

NameL-Phenylalaninamide,L-tyrosyl-D-alanylglycyl-N-[(1S)-1-(hydroxymethyl)-3-(methylsulfinyl)propyl]-Na-methyl-
CAS64854-64-4
SynonymsL-Phenylalaninamide,L-tyrosyl-D-alanylglycyl-N-[1-(hydroxymethyl)-3-(methylsulfinyl)propyl]-Na-methyl-, (1S)-;D-Ala2,MePhe4,Met5(O)]enkephalinol; DAMME; FK 33-824; FK 33824; SAN 33-824;Sandoz 33-824; Sandoz FK 33-824; [D-Ala2,N-methyl-Phe4,Met-(O)5-ol]-enkephalin
Molecular FormulaC29H41 N5 O7 S
Molecular Weight603.7301

refractive index1.607
storage temp−20°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :

SQ7315350

CHEMICAL NAME :

L-Phenylalaninamide, L-tyrosyl-D-alanylglycyl-N-(1-(hydroxymethyl)-3-(meth ylsulfinyl)propyl)- N(sup alpha)-methyl-, (1S)-

CAS REGISTRY NUMBER :

64854-64-4

LAST UPDATED :

199612

DATA ITEMS CITED :

2

MOLECULAR FORMULA :

C29-H41-N5-O7-S

MOLECULAR WEIGHT :

603.81

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intraperitoneal

DOSE :

60 mg/kg

SEX/DURATION :

female 9 day(s) after conception

TOXIC EFFECTS :

Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - Central Nervous System

REFERENCE :

TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 31,235,1985

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intraperitoneal

DOSE :

65 mg/kg

SEX/DURATION :

female 9 day(s) after conception

TOXIC EFFECTS :

Reproductive - Effects on Embryo or Fetus - fetal death

REFERENCE :

TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 31,235,1985