1H-Purine-2,6-dione,3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl)- cas no:6493-05-6
Synonyms: Theobromine,1-(5-oxohexyl)- (7CI,8CI);1-(5-Oxohexyl)-3,7-dimethylxanthine;1-(5-Oxohexyl)theobromine;3,7-Dihydro-3,7-dimethyl-1-(5-oxohexyl)-1H-purine-2,6-dione;3,7-Dimethyl-1-(5-oxohexyl)-1H,3H-purin-2,6-dione;3,7-Dimethyl-1-(5-oxohexyl)xanthine;Agapurin;Agapurin Retard;Azupentat;BL191;Dimethyloxohexylxanthine;Durapental;EHT 0202;NSC 637086;Oxpentifylline;Pentoxifyllin;Pentoxifylline;Pentoxiphyllin;Pentoxiphylline;Pentoxyfilline;Pentoxyphyllin;Pexal;Rentylin;Torental;Trental;Vasotal;Vazofirin;
Name1H-Purine-2,6-dione,3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl)-
CAS6493-05-6
SynonymsTheobromine,1-(5-oxohexyl)- (7CI,8CI);1-(5-Oxohexyl)-3,7-dimethylxanthine;1-(5-Oxohexyl)theobromine;3,7-Dihydro-3,7-dimethyl-1-(5-oxohexyl)-1H-purine-2,6-dione;3,7-Dimethyl-1-(5-oxohexyl)-1H,3H-purin-2,6-dione;3,7-Dimethyl-1-(5-oxohexyl)xanthine;Agapurin;Agapurin Retard;Azupentat;BL191;Dimethyloxohexylxanthine;Durapental;EHT 0202;NSC 637086;Oxpentifylline;Pentoxifyllin;Pentoxifylline;Pentoxiphyllin;Pentoxiphylline;Pentoxyfilline;Pentoxyphyllin;Pexal;Rentylin;Torental;Trental;Vasotal;Vazofirin;
EINECS(EC#)229-374-5
Molecular FormulaC13H18N4O3
Molecular Weight278.35
AppearanceWhite to off-white solid
storage tempStore at RT
Hazard Xn
Risk R22
Safety
Poison by subcutaneous, intravenous, and intraperitoneal routes. Moderately toxic by ingestion. Human systemic effects by ingestion: pulse rate decrease with fall in blood pressure. Human mutation data reported. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx
Safety Information of Pentoxyphylline (6493-05-6):
Hazard Codes: Xn
Xn: Harmful .gif)
Risk Statements: 22
22: Harmful if swallowed
Safety Statements: 36
36: Wear suitable protective clothing
WGK Germany: 3
RTECS: XH2475000
| 1. |
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dns-hmn:oth 1 mmol/L
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BIOJAU Biophysical Journal. 35 (1981),665. |
| 2. |
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dni-hmn:oth 4 mmol/L
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BIOJAU Biophysical Journal. 35 (1981),665. |
| 3. |
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orl-wmn TDLo:80 mg/kg:CVS
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BMJOAE British Medical Journal. 288 (1984),26. |
| 4. |
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orl-rat LD50:1170 mg/kg
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YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. 9 (1981),13. |
| 5. |
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ipr-rat LD50:230 mg/kg
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YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. 9 (1981),13. |
| 6. |
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scu-rat LD50:375 mg/kg
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OYYAA2 Oyo Yakuri. Pharmacometrics. 15 (1978),153. |
| 7. |
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ivn-rat LD50:231 mg/kg
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ARZNAD Arzneimittel-Forschung. Drug Research. 21 (1971),1446. |
| 8. |
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orl-mus LD50:1225 mg/kg
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NIIRDN “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),779. |
| 9. |
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ipr-mus LD50:239 mg/kg
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ARZNAD Arzneimittel-Forschung. Drug Research. 21 (1971),1446. |
| 10. |
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scu-mus LD50:480 mg/kg
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IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 8 (1977),267. |
