6493-05-6|1H-Purine-2,6-dione,3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl)-Products Supply

1H-Purine-2,6-dione,3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl)- cas no:6493-05-6

Synonyms: Theobromine,1-(5-oxohexyl)- (7CI,8CI);1-(5-Oxohexyl)-3,7-dimethylxanthine;1-(5-Oxohexyl)theobromine;3,7-Dihydro-3,7-dimethyl-1-(5-oxohexyl)-1H-purine-2,6-dione;3,7-Dimethyl-1-(5-oxohexyl)-1H,3H-purin-2,6-dione;3,7-Dimethyl-1-(5-oxohexyl)xanthine;Agapurin;Agapurin Retard;Azupentat;BL191;Dimethyloxohexylxanthine;Durapental;EHT 0202;NSC 637086;Oxpentifylline;Pentoxifyllin;Pentoxifylline;Pentoxiphyllin;Pentoxiphylline;Pentoxyfilline;Pentoxyphyllin;Pexal;Rentylin;Torental;Trental;Vasotal;Vazofirin;

Identification

Name1H-Purine-2,6-dione,3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl)-
CAS6493-05-6
SynonymsTheobromine,1-(5-oxohexyl)- (7CI,8CI);1-(5-Oxohexyl)-3,7-dimethylxanthine;1-(5-Oxohexyl)theobromine;3,7-Dihydro-3,7-dimethyl-1-(5-oxohexyl)-1H-purine-2,6-dione;3,7-Dimethyl-1-(5-oxohexyl)-1H,3H-purin-2,6-dione;3,7-Dimethyl-1-(5-oxohexyl)xanthine;Agapurin;Agapurin Retard;Azupentat;BL191;Dimethyloxohexylxanthine;Durapental;EHT 0202;NSC 637086;Oxpentifylline;Pentoxifyllin;Pentoxifylline;Pentoxiphyllin;Pentoxiphylline;Pentoxyfilline;Pentoxyphyllin;Pexal;Rentylin;Torental;Trental;Vasotal;Vazofirin;
EINECS(EC#)229-374-5
Molecular FormulaC₁₃H₁₈N₄O₃
Molecular Weight278.35

Chemical Properties

AppearanceWhite to off-white solid
storage tempStore at RT

Safety Data

Hazard Xn
Risk R22
Safety

Poison by subcutaneous, intravenous, and intraperitoneal routes. Moderately toxic by ingestion. Human systemic effects by ingestion: pulse rate decrease with fall in blood pressure. Human mutation data reported. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NO_x
Safety Information of Pentoxyphylline (6493-05-6):
Hazard Codes: Xn
Xn: Harmful
Risk Statements: 22
22: Harmful if swallowed
Safety Statements: 36
36: Wear suitable protective clothing
WGK Germany: 3
RTECS: XH2475000

Toxicity

1.	dns-hmn:oth 1 mmol/L	BIOJAU Biophysical Journal. 35 (1981),665.
2.	dni-hmn:oth 4 mmol/L	BIOJAU Biophysical Journal. 35 (1981),665.
3.	orl-wmn TDLo:80 mg/kg:CVS	BMJOAE British Medical Journal. 288 (1984),26.
4.	orl-rat LD50:1170 mg/kg	YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. 9 (1981),13.
5.	ipr-rat LD50:230 mg/kg	YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. 9 (1981),13.
6.	scu-rat LD50:375 mg/kg	OYYAA2 Oyo Yakuri. Pharmacometrics. 15 (1978),153.
7.	ivn-rat LD50:231 mg/kg	ARZNAD Arzneimittel-Forschung. Drug Research. 21 (1971),1446.
8.	orl-mus LD50:1225 mg/kg	NIIRDN “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),779.
9.	ipr-mus LD50:239 mg/kg	ARZNAD Arzneimittel-Forschung. Drug Research. 21 (1971),1446.
10.	scu-mus LD50:480 mg/kg	IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 8 (1977),267.

supplier list

THYKN (INDIA) INTERNATIONAL: Tel:+91-22-67033666 (3 lines); Address: 202, Kuntal, Mody Estate, Nr.Pipeline, LBS Road, Ghatkopar (West), Mumbai - 400086, India

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Suven Life Sciences Ltd.: Tel:+91-(40)-23541142, 23543311; Address: Serene Chambers, Road No. 7, Banjara Hills, Hyderabad, Andhra Pradesh 500034,

Varda Biotech Pvt. Ltd.: Tel:+91-(22)-6693 5686; Address: #110 & 111 Kartik Complex, New Link Road, Andheri (W), Mumbai, Maharashtra 400 053,

Lifeline Industries Limited: Tel:+91-(22)-2871 0505; Address: 3rd Floor, Mastermind III, Aarey Milk Colony, Goregaon East, Mumbai, Maharashtra 400065,

Advanced Compounds International, Inc.: Tel:+1-(845)-517-0135; Address: 119 Rockland Center, 300, Nanuet, New York 10954,

KINFON PHARMACEUTICAL AND CHEMICAL CO.LTD: Tel:86-23-8650081; Address: 32F,Duhe Plaza, Lijiatuo Street, Banan Dist,Chongq

Hubei XinRunde Chemical Co., Ltd: Tel:86-27-83214668; Address: East and West Lake District, Wuhan, China

Precious Chemical: Tel:+91-(22)-24980007 / 66607775; Address: 305, Nav Neelam Building, 108/ R. G. Thadani Marg, Worli Seaface, Mumbai, Maharashtra 400 018,

1H-Purine-2,6-dione,3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl)- cas no:6493-05-6

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