6493-05-6|1H-Purine-2,6-dione,3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl)-Products Supply

1H-Purine-2,6-dione,3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl)- cas no:6493-05-6

Synonyms: Theobromine,1-(5-oxohexyl)- (7CI,8CI);1-(5-Oxohexyl)-3,7-dimethylxanthine;1-(5-Oxohexyl)theobromine;3,7-Dihydro-3,7-dimethyl-1-(5-oxohexyl)-1H-purine-2,6-dione;3,7-Dimethyl-1-(5-oxohexyl)-1H,3H-purin-2,6-dione;3,7-Dimethyl-1-(5-oxohexyl)xanthine;Agapurin;Agapurin Retard;Azupentat;BL191;Dimethyloxohexylxanthine;Durapental;EHT 0202;NSC 637086;Oxpentifylline;Pentoxifyllin;Pentoxifylline;Pentoxiphyllin;Pentoxiphylline;Pentoxyfilline;Pentoxyphyllin;Pexal;Rentylin;Torental;Trental;Vasotal;Vazofirin;

Identification

Name1H-Purine-2,6-dione,3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl)-
CAS6493-05-6
SynonymsTheobromine,1-(5-oxohexyl)- (7CI,8CI);1-(5-Oxohexyl)-3,7-dimethylxanthine;1-(5-Oxohexyl)theobromine;3,7-Dihydro-3,7-dimethyl-1-(5-oxohexyl)-1H-purine-2,6-dione;3,7-Dimethyl-1-(5-oxohexyl)-1H,3H-purin-2,6-dione;3,7-Dimethyl-1-(5-oxohexyl)xanthine;Agapurin;Agapurin Retard;Azupentat;BL191;Dimethyloxohexylxanthine;Durapental;EHT 0202;NSC 637086;Oxpentifylline;Pentoxifyllin;Pentoxifylline;Pentoxiphyllin;Pentoxiphylline;Pentoxyfilline;Pentoxyphyllin;Pexal;Rentylin;Torental;Trental;Vasotal;Vazofirin;
EINECS(EC#)229-374-5
Molecular FormulaC₁₃H₁₈N₄O₃
Molecular Weight278.35

Chemical Properties

AppearanceWhite to off-white solid
storage tempStore at RT

Safety Data

Hazard Xn
Risk R22
Safety

Poison by subcutaneous, intravenous, and intraperitoneal routes. Moderately toxic by ingestion. Human systemic effects by ingestion: pulse rate decrease with fall in blood pressure. Human mutation data reported. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NO_x
Safety Information of Pentoxyphylline (6493-05-6):
Hazard Codes: Xn
Xn: Harmful
Risk Statements: 22
22: Harmful if swallowed
Safety Statements: 36
36: Wear suitable protective clothing
WGK Germany: 3
RTECS: XH2475000

Toxicity

1.	dns-hmn:oth 1 mmol/L	BIOJAU Biophysical Journal. 35 (1981),665.
2.	dni-hmn:oth 4 mmol/L	BIOJAU Biophysical Journal. 35 (1981),665.
3.	orl-wmn TDLo:80 mg/kg:CVS	BMJOAE British Medical Journal. 288 (1984),26.
4.	orl-rat LD50:1170 mg/kg	YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. 9 (1981),13.
5.	ipr-rat LD50:230 mg/kg	YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. 9 (1981),13.
6.	scu-rat LD50:375 mg/kg	OYYAA2 Oyo Yakuri. Pharmacometrics. 15 (1978),153.
7.	ivn-rat LD50:231 mg/kg	ARZNAD Arzneimittel-Forschung. Drug Research. 21 (1971),1446.
8.	orl-mus LD50:1225 mg/kg	NIIRDN “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),779.
9.	ipr-mus LD50:239 mg/kg	ARZNAD Arzneimittel-Forschung. Drug Research. 21 (1971),1446.
10.	scu-mus LD50:480 mg/kg	IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 8 (1977),267.

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Gyma Laboratories Of America, Inc.: Tel:+1-516-933-0900; Address: 135 Cantiague Rock Rd.Westbury, NY 11590

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farchemia srl: Tel:+39-0363-31401; Address: via bergamo 121 24047 treviglio bg

1H-Purine-2,6-dione,3,7-dihydro-3,7-dimethyl-1-(5-oxohexyl)- cas no:6493-05-6

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