64953-12-4|5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R)-2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,sodium salt (1:2), (6R,7R)-Products Supply

5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R)-2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,sodium salt (1:2), (6R,7R)- cas no:64953-12-4

Synonyms: 5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R)-carboxy(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,disodium salt, (6R,7R)- (9CI);6059S;Antibiotic 6059S;Disodium latamoxef;Festamoxin;LY 12735;LY 127935;Latamoxef sodium;Moxalactam disodium;S 6059;Shiomarin;Shionogi 6059S;

Identification

Name5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R)-2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,sodium salt (1:2), (6R,7R)-
CAS64953-12-4
Synonyms5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R)-carboxy(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,disodium salt, (6R,7R)- (9CI);6059S;Antibiotic 6059S;Disodium latamoxef;Festamoxin;LY 12735;LY 127935;Latamoxef sodium;Moxalactam disodium;S 6059;Shiomarin;Shionogi 6059S;
EINECS(EC#)265-288-4
Molecular FormulaC₂₀H₁₈N₆Na₂O₉S
Molecular Weight564.48

Chemical Properties

storage temp2-8°C

Safety Data

Hazard Xn:Harmful
Risk R42/43
Safety

Mildly toxic by several routes. An experimental teratogen. Other experimental reproductive effects. Human systemic effects: ulceration or bleeding from small and large intestine, hemorrhage, thrombocytopenia. When heated to decomposition it emits toxic fumes of SO_x, NO_x, and Na₂O.
Hazard Codes:
Xn: Harmful
Risk Statements about Latamoxef sodium (64953-12-4):
R42/43: May cause sensitization by inhalation and skin contact.
Safety Statements about Latamoxef sodium (64953-12-4):
S22 Do not breathe dust.
S45 In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37: Wear suitable protective clothing and gloves.

Toxicity

1.	???	orl-man TDLo:571?mg/kg/20D-I:GIT	???	JAMAAP ?? JAMA, Journal of the American Medical Association. 250 (1983),730.
2.	???	ivn-man LDLo:371?mg/kg/17D-I:BLD	???	DICPBB ?? Drug Intelligence and Clinical Pharmacy. 18 (1984),140.
3.	???	ivn-man TDLo:1143?mg/kg/10D-I:BLD	???	DICPBB ?? Drug Intelligence and Clinical Pharmacy. 18 (1984),721.
4.	???	ipr-rat LD50:8100?mg/kg	???	NIIRDN ?? Drugs in Japan. Ethical Drugs, 6th Edition 1982 6 (1982),APP-21.
5.	???	scu-rat LD50:9000?mg/kg	???	NIIRDN ?? Drugs in Japan. Ethical Drugs, 6th Edition 1982 6 (1982),APP-21.
6.	???	ivn-rat LD50:5500?mg/kg	???	NIIRDN ?? Drugs in Japan. Ethical Drugs, 6th Edition 1982 6 (1982),APP-21.
7.	???	ipr-mus LD50:8100?mg/kg	???	NIIRDN ?? Drugs in Japan. Ethical Drugs, 6th Edition 1982 6 (1982),APP-21.
8.	???	scu-mus LD50:9000?mg/kg	???	NIIRDN ?? Drugs in Japan. Ethical Drugs, 6th Edition 1982 6 (1982),APP-21.
9.	???	ivn-mus LD50:5500?mg/kg	???	NIIRDN ?? Drugs in Japan. Ethical Drugs, 6th Edition 1982 6 (1982),APP-21.

supplier list

Taizhou Creating Chemical Co. ,Ltd.: Tel:+86-(576)-88827176,88820069; Address: B Suite 12F,JiangbinBuilding,Jiaojiang, Taizhou, Zhejiang,

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Taizhou Xingcheng Chempharm Co., Ltd.: Tel:+86-(576)-88886292, 88525005; Address: B Area. 10 Floor.Yaodadasha. 289#.Shifu Road, Taizhou, Zhejiang 318000,

Xilin Chemical Group Co., Ltd: Tel:+86-(0)-15527136576; Address: 16# Luojiashan, Wuchang District, Wuhan, Hubei 430071,

Kouting Chemical Co.,Ltd: Tel:+86-(21)-58116473; Address: Hunan Road, Pudong New District, Shanghai, Shanghai 201318,

KINFON PHARMACEUTICAL AND CHEMICAL CO.LTD: Tel:86-23-8650081; Address: 32F,Duhe Plaza, Lijiatuo Street, Banan Dist,Chongq

Hainan Shunyuan Chemtech. Co., Ltd: Tel:+86-0898-68529231 68529232; Address: Hainan,china

HangZhou Peak Chemical Co.,Ltd: Tel:+86-571-88233073; Address: Rm. 3-502,Building 3 Tucuiyuan,Lakeside Garden,No.176 Wenyi West Road, HangZhou,China

Shanghai Hao Su Chem-Tech lnc.: Tel:021-6661 0036 021-5653 8833; Address: 201-204,2 BLDG,1009 North Zhong Shan Road, Shanghai

VETCHEM Biochemistry Science: Tel:+86-21-593837; Address: No.2 Jinshanwei Industrial Zon,Shanghai 200120 China

Wujiang Yingchuang Chemical Co., Ltd.: Tel:+86-(25)-8645 8768; Address: 215 Ying Tian Da Street, JianYe, Nanjing, Jiangsu 210017,

AOPHARM: Tel:86-311-66600578; Address: C-2103 Wonder Business Square, 15 Yuhua West Rd.

Jinan Haohua Industry Co., Ltd.: Tel:0086-531-58773055; Address: No.59 Gongye South RD

Nanjing Norris-Pharm Technology Co., Ltd.: Tel:86-25-66112885; Address: 2rd Qiande Road Jiangning Life&Science Park Nanjin

5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R)-2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,sodium salt (1:2), (6R,7R)- cas no:64953-12-4

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