5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R)-2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,sodium salt (1:2), (6R,7R)- cas no:64953-12-4
Synonyms: 5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R)-carboxy(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,disodium salt, (6R,7R)- (9CI);6059S;Antibiotic 6059S;Disodium latamoxef;Festamoxin;LY 12735;LY 127935;Latamoxef sodium;Moxalactam disodium;S 6059;Shiomarin;Shionogi 6059S;
Name5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R)-2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,sodium salt (1:2), (6R,7R)-
CAS64953-12-4
Synonyms5-Oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R)-carboxy(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-,disodium salt, (6R,7R)- (9CI);6059S;Antibiotic 6059S;Disodium latamoxef;Festamoxin;LY 12735;LY 127935;Latamoxef sodium;Moxalactam disodium;S 6059;Shiomarin;Shionogi 6059S;
EINECS(EC#)265-288-4
Molecular FormulaC20H18N6Na2O9S
Molecular Weight564.48
storage temp2-8°C
Hazard Xn:Harmful
Risk R42/43
Safety
Mildly toxic by several routes. An experimental teratogen. Other experimental reproductive effects. Human systemic effects: ulceration or bleeding from small and large intestine, hemorrhage, thrombocytopenia. When heated to decomposition it emits toxic fumes of SOx, NOx, and Na2O.
Hazard Codes:
Xn: Harmful .gif)
Risk Statements about Latamoxef sodium (64953-12-4):
R42/43: May cause sensitization by inhalation and skin contact.
Safety Statements about Latamoxef sodium (64953-12-4):
S22 Do not breathe dust.
S45 In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37: Wear suitable protective clothing and gloves.
| 1. |
??? |
orl-man TDLo:571?mg/kg/20D-I:GIT
|
??? |
JAMAAP ?? JAMA, Journal of the American Medical Association. 250 (1983),730. |
| 2. |
??? |
ivn-man LDLo:371?mg/kg/17D-I:BLD
|
??? |
DICPBB ?? Drug Intelligence and Clinical Pharmacy. 18 (1984),140. |
| 3. |
??? |
ivn-man TDLo:1143?mg/kg/10D-I:BLD
|
??? |
DICPBB ?? Drug Intelligence and Clinical Pharmacy. 18 (1984),721. |
| 4. |
??? |
ipr-rat LD50:8100?mg/kg
|
??? |
NIIRDN ?? Drugs in Japan. Ethical Drugs, 6th Edition 1982 6 (1982),APP-21. |
| 5. |
??? |
scu-rat LD50:9000?mg/kg
|
??? |
NIIRDN ?? Drugs in Japan. Ethical Drugs, 6th Edition 1982 6 (1982),APP-21. |
| 6. |
??? |
ivn-rat LD50:5500?mg/kg
|
??? |
NIIRDN ?? Drugs in Japan. Ethical Drugs, 6th Edition 1982 6 (1982),APP-21. |
| 7. |
??? |
ipr-mus LD50:8100?mg/kg
|
??? |
NIIRDN ?? Drugs in Japan. Ethical Drugs, 6th Edition 1982 6 (1982),APP-21. |
| 8. |
??? |
scu-mus LD50:9000?mg/kg
|
??? |
NIIRDN ?? Drugs in Japan. Ethical Drugs, 6th Edition 1982 6 (1982),APP-21. |
| 9. |
??? |
ivn-mus LD50:5500?mg/kg
|
??? |
NIIRDN ?? Drugs in Japan. Ethical Drugs, 6th Edition 1982 6 (1982),APP-21. |
