65-23-6|3,4-Pyridinedimethanol,5-hydroxy-6-methyl-Products Supply

3,4-Pyridinedimethanol,5-hydroxy-6-methyl- cas no:65-23-6

Synonyms: Pyridoxol(8CI);2-Methyl-3-hydroxy-4,5-di(hydroxymethyl)pyridine;2-Methyl-4,5-bis(hydroxymethyl)-3-hydroxypyridine;5-Hydroxy-6-methyl-3,4-pyridinedimethanol;Adermin;Bezatin;Pirivitol;Pyridoxin;VB6;

Identification

Name3,4-Pyridinedimethanol,5-hydroxy-6-methyl-
CAS65-23-6
SynonymsPyridoxol(8CI);2-Methyl-3-hydroxy-4,5-di(hydroxymethyl)pyridine;2-Methyl-4,5-bis(hydroxymethyl)-3-hydroxypyridine;5-Hydroxy-6-methyl-3,4-pyridinedimethanol;Adermin;Bezatin;Pirivitol;Pyridoxin;VB6;
EINECS(EC#)200-603-0
Molecular FormulaC₈H₁₁NO₃
Molecular Weight169.20

Chemical Properties

Appearancecrystalline solid
storage temp2-8°C

Safety Data

Hazard Xi
Risk R36/37/38
Safety

Moderately toxic by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Human systemic effects: ataxia, local anesthetic, paresthesia. When heated to decomposition it emits toxic fumes of NO_x.
Hazard Codes: Irritant Xi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
WGK Germany: 3
RTECS of Pyridoxine (CAS NO.65-23-6): UV1350000

HS Code 29362500

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
man	TDLo	oral	5143mg/kg/17W (5143mg/kg)	PERIPHERAL NERVE AND SENSATION: LOCAL ANESTHETIC	New England Journal of Medicine. Vol. 309, Pg. 445, 1983.
mouse	LD50	intraperitoneal	966mg/kg (966mg/kg)		Farmakologiya i Toksikologiya Vol. 40, Pg. 371, 1977.
mouse	LD50	intravenous	545mg/kg (545mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 10, Pg. 683, 1960.
rat	LD50	intraperitoneal	1500mg/kg (1500mg/kg)	LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Proceedings of the European Society for the Study of Drug Toxicity. Vol. 4, Pg. 179, 1964.
rat	LD50	intravenous	657mg/kg (657mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Proceedings of the Society for Experimental Biology and Medicine. Vol. 44, Pg. 147, 1940.
rat	LD50	oral	4gm/kg (4000mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Proceedings of the Society for Experimental Biology and Medicine. Vol. 43, Pg. 116, 1940.
rat	LD50	subcutaneous	3100mg/kg (3100mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Proceedings of the Society for Experimental Biology and Medicine. Vol. 43, Pg. 116, 1940.
women	TDLo	oral	139mg/kg/5Y-I (139mg/kg)	PERIPHERAL NERVE AND SENSATION: PARESTHESIS	New England Journal of Medicine. Vol. 311, Pg. 986, 1984.
women	TDLo	oral	2100mg/kg/30D (2100mg/kg)	PERIPHERAL NERVE AND SENSATION: PARESTHESIS BEHAVIORAL: ATAXIA	Neurology. Vol. 35, Pg. 1466, 1985.
women	TDLo	oral	4800mg/kg/17W (4800mg/kg)	PERIPHERAL NERVE AND SENSATION: LOCAL ANESTHETIC	New England Journal of Medicine. Vol. 309, Pg. 445, 1983.

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3,4-Pyridinedimethanol,5-hydroxy-6-methyl- cas no:65-23-6

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