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Nicotine ditartrate cas no:65-31-6

Synonyms: 3-[(2S)-1-Methylpyrrolidin-2-yl]pyridine ditartrate

Identification
NameNicotine ditartrate
CAS65-31-6
Synonyms3-[(2S)-1-Methylpyrrolidin-2-yl]pyridine ditartrate
EINECS(EC#)200-607-2
Molecular FormulaC10H14N2.2(C4H6O6)
Molecular Weight462.46
Chemical Properties
AppearanceA reddish white crystalline solid.
storage tempStore in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Poison room locked.
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(a)
Safety Data

Hazard T+,N
Risk 26/27/28-51/53
Safety

Hazard codes:
T+: Very toxic
N: Dangerous for the environment
Risk Statements:
R26/27/28: Very toxic by inhalation, in contact with skin and if swallowed.
R51/53: Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements:
S13: Keep away from food, drink and animal foodstuffs.
S28: After contact with skin, wash immediately with plenty of soap-suds. 
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S61: Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: UN 1659 6.1/PG 2
WGK Germany: 2
RTECS: QT0350000
HazardClass: 6.1(a)
PackingGroup: II
Hazardous Substances Data: 65-31-6(Hazardous Substances Data)


Toxicity

Organism

Test Type

Route

Reported Dose (Normalized Dose)

Effect

Source

frog

LD50

parenteral

337mg/kg (337mg/kg)

 

Acta Biologica et Medica Germanica. Vol. 28, Pg. 681, 1972.

hamster

LD50

intraperitoneal

125mg/kg (125mg/kg)

 

Toxicology and Applied Pharmacology. Vol. 22, Pg. 324, 1972.

mouse

LD50

intraperitoneal

9100ug/kg (9.1mg/kg)

 

Toxicology and Applied Pharmacology. Vol. 65, Pg. 366, 1982.

mouse

LD50

intravenous

300ug/kg (0.3mg/kg)

Behavioral: convulsions or effect on seizure thresholdbehavioral: regidity

British Journal of Pharmacology. Vol. 35, Pg. 161, 1969.

mouse

LD50

oral

65mg/kg (65mg/kg)

 

Pharmacological Research Communications. Vol. 5, Pg. 341, 1973.

mouse

LD50

subcutaneous

53mg/kg (53mg/kg)

 

Pharmacological Research Communications. Vol. 5, Pg. 341, 1973.

rat

LD50

intraperitoneal

83mg/kg (83mg/kg)

 

Toxicology and Applied Pharmacology. Vol. 22, Pg. 324, 1972.

rat

LD50

intravenous

600mg/kg (600mg/kg)

Behavioral: convulsions or effect on seizure threshold

Pharmacological Research Communications. Vol. 5, Pg. 341, 1973.

rat

LD50

oral

65mg/kg (65mg/kg)

 

Pharmacological Research Communications. Vol. 5, Pg. 341, 1973.

rat

LD50

parenteral

33500ug/kg (33.5mg/kg)

 

Acta Biologica et Medica Germanica. Vol. 28, Pg. 681, 1972.

rat

LD50

unreported

30mg/kg (30mg/kg)

 

Schweizerische Medizinische Wochenschrift. Vol. 91, Pg. 359, 1961.

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Nanjing Bangnuo Biotechnology Co., Ltd
Tel:86-1732-7098554
Address: shuanglong road,jiangning, nanjing,jiangsu
Hubei XinRunde Chemical Co., Ltd
Tel:86-27-83214668
Address: East and West Lake District, Wuhan, China
Hubei XinRunde Chemical Co., Ltd
Tel:86-27-83214668
Address: East and West Lake District, Wuhan, China
Hubei XinRunde Chemical Co., Ltd
Tel:86-27-83214668
Address: East and West Lake District, Wuhan, China
china haorun industry group co.,ltd
Tel:86-311-68070939
Address: NO.120 Shengli North Road, Changan District, Shijiazhuang City, China
Boc Sciences
Tel:1-631-5046093
Address: 45-16 Ramsey Road Shirley, NY 11967, USA

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