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Salicylamide cas no:65-45-2

Synonyms: Salamide;Saliamid;Saliamin;Salicim;Salicylic acid amide;Salipur;Salizell;Salrin;Salymid;Samid;Serramida;Urtosal;o-Hydroxybenzamide;Benzamide,2-hydroxy-;Salicylamide(8CI);2-Carbamoylphenol;2-Carboxamidophenol;2-Hydroxybenzamide;Afko-Sal;Algamon;Algiamida;Allevin;Amid-Sal;Amidosal;Anamid;Benesal;Cetamide;Cidal;Dropsprin;Liquiprin;Morsarinas;Novecyl;Oramid;Panithal;Raspberin;Salamid;

Identification
NameSalicylamide
CAS65-45-2
SynonymsSalamide;Saliamid;Saliamin;Salicim;Salicylic acid amide;Salipur;Salizell;Salrin;Salymid;Samid;Serramida;Urtosal;o-Hydroxybenzamide;Benzamide,2-hydroxy-;Salicylamide(8CI);2-Carbamoylphenol;2-Carboxamidophenol;2-Hydroxybenzamide;Afko-Sal;Algamon;Algiamida;Allevin;Amid-Sal;Amidosal;Anamid;Benesal;Cetamide;Cidal;Dropsprin;Liquiprin;Morsarinas;Novecyl;Oramid;Panithal;Raspberin;Salamid;
EINECS(EC#)200-609-3
Molecular FormulaC7H7NO2
Molecular Weight137.13598
Chemical Properties
Appearancewhite to pink crystalline powder
refractive index1.562 (20 C)
storage tempStore at 2 - 8 C. Keep container tightly closed.
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard Xn:Harmful
Risk R22
Safety

Hazard Codes:?Xn
Risk Statements: 22-36/37/38-20/21/22?
R22:Harmful if swallowed.?
R36/37/38:Irritating to eyes, respiratory system and skin.?
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 26-36?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36:Wear suitable protective clothing.
RIDADR: 3249
WGK Germany: 3
RTECS: VN6475000
HazardClass: 6.1(b)
PackingGroup of Salicylamide (CAS NO.65-45-2): III


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo intraperitoneal 1gm/kg (1000mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Journal of Pharmacology and Experimental Therapeutics. Vol. 101, Pg. 119, 1951.
cat LDLo oral 150mg/kg (150mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 5, Pg. 572, 1955.
dog LDLo intraperitoneal 1gm/kg (1000mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Journal of Pharmacology and Experimental Therapeutics. Vol. 101, Pg. 119, 1951.
guinea pig LD50 oral 1730mg/kg (1730mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: TREMOR

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 47, Pg. 479, 1958.
guinea pig LDLo intraperitoneal 1gm/kg (1000mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Journal of Pharmacology and Experimental Therapeutics. Vol. 101, Pg. 119, 1951.
mouse LD50 intraperitoneal 180mg/kg (180mg/kg) ? Bollettino Chimico Farmaceutico. Vol. 111, Pg. 293, 1972.
mouse LD50 intravenous 313mg/kg (313mg/kg) BEHAVIORAL: GENERAL ANESTHETIC Journal of Pharmacology and Experimental Therapeutics. Vol. 101, Pg. 119, 1951.
mouse LD50 oral 300mg/kg (300mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 5, Pg. 572, 1955.
mouse LD50 subcutaneous 300mg/kg (300mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 8, Pg. 25, 1958.
rabbit LD50 oral 3200mg/kg (3200mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 5, Pg. 572, 1955.
rabbit LDLo intraperitoneal 1gm/kg (1000mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Journal of Pharmacology and Experimental Therapeutics. Vol. 101, Pg. 119, 1951.
rat LD50 intraperitoneal 600mg/kg (600mg/kg) ? Journal of Pharmacology and Experimental Therapeutics. Vol. 108, Pg. 450, 1953.
rat LD50 oral 980mg/kg (980mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 47, Pg. 479, 1958.

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