4-Pyrimidinecarboxylicacid, 1,2,3,6-tetrahydro-2,6-dioxo- cas no:65-86-1
Synonyms: Orotic acid(8CI);1,2,3,6-Tetrahydro-2,6-dioxo-4-pyrimidinecarboxylic acid;2,4-Dihydroxypyrimidine-6-carboxylic acid;2,6-Dihydroxy-4-pyrimidinecarboxylicacid;2,6-Dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid;6-Carboxyuracil;6-Uracilcarboxylic acid;Animal galactose factor;NSC 79560;NSC 9791;Orodin;Orotonin;Oroturic;Orotyl;Vitamin B13;Whey factor;
Name4-Pyrimidinecarboxylicacid, 1,2,3,6-tetrahydro-2,6-dioxo-
CAS65-86-1
SynonymsOrotic acid(8CI);1,2,3,6-Tetrahydro-2,6-dioxo-4-pyrimidinecarboxylic acid;2,4-Dihydroxypyrimidine-6-carboxylic acid;2,6-Dihydroxy-4-pyrimidinecarboxylicacid;2,6-Dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid;6-Carboxyuracil;6-Uracilcarboxylic acid;Animal galactose factor;NSC 79560;NSC 9791;Orodin;Orotonin;Oroturic;Orotyl;Vitamin B13;Whey factor;
EINECS(EC#)200-619-8
Molecular FormulaC5H4N2O4
Molecular Weight156.1
Appearancewhite crystalline powder
storage tempKeep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Hazard Xn:Harmful
Risk R22;R36/37/38
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- RM3180000
- CHEMICAL NAME :
- Orotic acid
- CAS REGISTRY NUMBER :
- 65-86-1
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C5-H4-N2-O4
- MOLECULAR WEIGHT :
- 156.11
- WISWESSER LINE NOTATION :
- T6MVMVJ FVQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 841 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 770 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- Morphological transformation
- TYPE OF TEST :
- DNA inhibition
MUTATION DATA
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Rodent - rat Liver
- DOSE/DURATION :
- 120 umol/L
- REFERENCE :
- CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980-
Volume(issue)/page/year: 9,675,1988
