Norgestrel cas no:6533-00-2
Synonyms: Norgestrel [USAN:INN:BAN:JAN]; (+-)-13-Ethyl-17-hydroxy-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one; dl-13-beta-Ethyl-17-alpha-ethynyl-17-beta-hydroxygon-4-en-3-one; dl-13-beta-Ethyl-17-alpha-ethynyl-19-nortestosterone; 18,19-Dinor-17-alpha-pregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-, (+-)-; 18,19-Dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-,(17alpha)-(+-)-; Norgestrel (DL-)
NameNorgestrel
CAS6533-00-2
SynonymsNorgestrel [USAN:INN:BAN:JAN]; (+-)-13-Ethyl-17-hydroxy-18,19-dinor-17alpha-pregn-4-en-20-yn-3-one; dl-13-beta-Ethyl-17-alpha-ethynyl-17-beta-hydroxygon-4-en-3-one; dl-13-beta-Ethyl-17-alpha-ethynyl-19-nortestosterone; 18,19-Dinor-17-alpha-pregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-, (+-)-; 18,19-Dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-,(17alpha)-(+-)-; Norgestrel (DL-)
EINECS(EC#)229-433-5
Molecular FormulaC21H28O2
Molecular Weight312.45
Appearancewhite crystalline powder
refractive index1.571
storage temp2-8°C
Hazard Xn:Harmful
Risk R20/21/22;R40
Safety
Human reproductive effects by ingestion and implant: menstrual cycle changes or disorders and female fertility index changes. An experimental teratogen. Experimental reproductive effects. Questionable carcinogen with experimental neoplastigenic data. An oral contraceptive. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Codes:Xn
Xn:Harmful
Risk Statements
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R40:Limited evidence of a carcinogenic effect.
Safety Statements
S22:Do not breathe dust .
S36:Wear suitable protective clothing .
WGK Germany:3
RTECS:JF8259000
Hazardous Substances Data:6533-00-2(Hazardous Substances Data)
| 1. |
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scu-rat TDLo:60 mg/kg (female 17-20D post):TER
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AVBIB9 Advances in the Biosciences. 13 (1974),71. |
| 2. |
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orl-mus TDLo:57 mg/kg/68W-C:NEO
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CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. 168 (1974),1190. |
| 3. |
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orl-rat LD50:5010 mg/kg
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TXAPA9 Toxicology and Applied Pharmacology. 18 (1971),185. |
| 4. |
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ipr-rat LD50:11,200 mg/kg
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YKYUA6 Yakkyoku. Pharmacy. 29 (1978),1479. |
| 5. |
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orl-mus LD50:5010 mg/kg
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TXAPA9 Toxicology and Applied Pharmacology. 18 (1971),185. |
| 6. |
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ipr-mus LD50:7300 mg/kg
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YKYUA6 Yakkyoku. Pharmacy. 29 (1978),1479. |
