1,3,5-Triazin-2(1H)-one,4-amino-1-b-D-arabinofuranosyl- cas no:65886-71-7

Name1,3,5-Triazin-2(1H)-one,4-amino-1-b-D-arabinofuranosyl-
CAS65886-71-7
Synonyms1-b-D-Arabinofuranosyl-5-azacytosine;5-Aza-1-arabinosylcytosine; 5-Azacytosine arabinoside; Fazarabine; Kymarabine;NSC 281272; ara-AC
Molecular FormulaC8H12 N4 O5
Molecular Weight244.20

refractive index1.823

CHEMICAL IDENTIFICATION

RTECS NUMBER :

XZ2854400

CHEMICAL NAME :

s-Triazin-2(1H)-one, 4-amino-1-beta-D-arabinofuranosyl-

CAS REGISTRY NUMBER :

65886-71-7

LAST UPDATED :

199206

DATA ITEMS CITED :

4

MOLECULAR FORMULA :

C8-H12-N4-O5

MOLECULAR WEIGHT :

244.24

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Human

DOSE/DURATION :

1557 ug/kg/72H-C

TOXIC EFFECTS :

Gastrointestinal - nausea or vomiting Blood - agranulocytosis

MUTATION DATA

TYPE OF TEST :

DNA inhibition

TEST SYSTEM :

Rodent - mouse Leukocyte

DOSE/DURATION :

2 umol/L

REFERENCE :

PAACA3 Proceedings of the American Association for Cancer Research. (Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 1954- Volume(issue)/page/year: 24,297,1983