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Dienogestrel cas no:65928-58-7

Synonyms: 17a-Cyanomethyl-17b-hydroxyestra-4, 9-dien-3-one;Dienogest;Dienogestril;Dinagest;19-Norpregna-4,9-diene-21-nitrile,17-hydroxy-3-oxo-, (17a)-;

Identification
NameDienogestrel
CAS65928-58-7
Synonyms17a-Cyanomethyl-17b-hydroxyestra-4, 9-dien-3-one;Dienogest;Dienogestril;Dinagest;19-Norpregna-4,9-diene-21-nitrile,17-hydroxy-3-oxo-, (17a)-;
Molecular FormulaC20H25NO2
Molecular Weight311.418
Chemical Properties
AppearancePale Yellow Solid
refractive index1.589
storage temp-20°C Freezer
Safety Data

Safety

Moderately toxic by ingestion, subcutaneous, and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx and CN?.


Toxicity
1. ???

dlt-mus-scu 700?mg/kg/35D

??? ENDKAC ?? Endokrinologie. 76 (1980),13.
2. ???

orl-mus TDLo:500?mg/kg (female 13-17D post):TER

??? EXCEDS ?? Experimental and Clinical Endocrinology. 81 (1983),197.
3. ???

orl-mus LD50:4000?mg/kg

??? PHARAT ?? Pharmazie. 34 (1979),319.
4. ???

ipr-mus LDLo:1?g/kg

??? EXCEDS ?? Experimental and Clinical Endocrinology. 81 (1983),175.
5. ???

scu-mus LDLo:5000?mg/kg

??? PHARAT ?? Pharmazie. 34 (1979),319.
6. ???

orl-rbt LDLo:1?g/kg

??? EXCEDS ?? Experimental and Clinical Endocrinology. 81 (1983),175.
7. ???

ipr-rbt LDLo:1500?mg/kg

??? EXCEDS ?? Experimental and Clinical Endocrinology. 81 (1983),175.

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