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Uracil cas no:66-22-8

Synonyms: SQ 7726;Urazil;pyrimidine-2,4(1H,3H)-dione;2,4-Pyrimidinediol;2,4-Pyrimidinedione;2,4-Dihydroxypyrimidine;4-hydroxy-2(1H)-pyrimidinone;2,4-Dihydroxypyrimidine(Uracil);BMS 205603-01;2,4(1H,3H)-Pyrimidinedione (9CI);2,4-(1H,3H)-pyrimidinedione (9CI);RU 12709;Uracil (8CI);SQ 6201;2,4(1H,3H)-pyrimidinedione;2, 4 (1H,3H)-Pyrimidinedione;2-hydroxy-4(1H)-pyrimidinone;Uracil (JAN/USAN);2,4-Dioxopyrimidine;Hybar X;Pyrod;Ura;Pirod;SQ 8493;1H-pyrimidine-2,4-dione;2, 4-Dioxopyrimidine;Pyrimidine-2,4-diol;

Identification
NameUracil
CAS66-22-8
SynonymsSQ 7726;Urazil;pyrimidine-2,4(1H,3H)-dione;2,4-Pyrimidinediol;2,4-Pyrimidinedione;2,4-Dihydroxypyrimidine;4-hydroxy-2(1H)-pyrimidinone;2,4-Dihydroxypyrimidine(Uracil);BMS 205603-01;2,4(1H,3H)-Pyrimidinedione (9CI);2,4-(1H,3H)-pyrimidinedione (9CI);RU 12709;Uracil (8CI);SQ 6201;2,4(1H,3H)-pyrimidinedione;2, 4 (1H,3H)-Pyrimidinedione;2-hydroxy-4(1H)-pyrimidinone;Uracil (JAN/USAN);2,4-Dioxopyrimidine;Hybar X;Pyrod;Ura;Pirod;SQ 8493;1H-pyrimidine-2,4-dione;2, 4-Dioxopyrimidine;Pyrimidine-2,4-diol;
EINECS(EC#)200-621-9
Molecular FormulaC4H4N2O2
Molecular Weight112.09
Chemical Properties
Appearancefine off-white crystalline powder
refractive index1.501
storage tempKeep tightly closed. Keep away from heat, sparks, and open flame.
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass4.2
Safety Data

Hazard UN NO.
Safety

Moderately toxic by intraperitoneal route. An experimental teratogen. Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes of Uracil (CAS NO.66-22-8):?Xi
WGK Germany:?2
Safety Statements:?22-24/25?
S22: Do not breathe dust.?
S24/25: Avoid contact with skin and eyes.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 oral > 5gm/kg (5000mg/kg) ? Medicamentos de Actualidad. Vol. 21, Pg. 125, 1985.
mouse LD50 intraperitoneal 1513mg/kg (1513mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
Journal of Pharmacology and Experimental Therapeutics. Vol. 207, Pg. 504, 1978.
mouse LD50 oral > 8gm/kg (8000mg/kg) ? Oyo Yakuri. Pharmacometrics. Vol. 20, Pg. 1009, 1980.
rabbit LD50 oral > 10gm/kg (10000mg/kg) ? Medicamentos de Actualidad. Vol. 21, Pg. 125, 1985.
rat LD50 oral > 6gm/kg (6000mg/kg) ? Medicamentos de Actualidad. Vol. 21, Pg. 125, 1985.

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