Uracil cas no:66-22-8
Synonyms: SQ 7726;Urazil;pyrimidine-2,4(1H,3H)-dione;2,4-Pyrimidinediol;2,4-Pyrimidinedione;2,4-Dihydroxypyrimidine;4-hydroxy-2(1H)-pyrimidinone;2,4-Dihydroxypyrimidine(Uracil);BMS 205603-01;2,4(1H,3H)-Pyrimidinedione (9CI);2,4-(1H,3H)-pyrimidinedione (9CI);RU 12709;Uracil (8CI);SQ 6201;2,4(1H,3H)-pyrimidinedione;2, 4 (1H,3H)-Pyrimidinedione;2-hydroxy-4(1H)-pyrimidinone;Uracil (JAN/USAN);2,4-Dioxopyrimidine;Hybar X;Pyrod;Ura;Pirod;SQ 8493;1H-pyrimidine-2,4-dione;2, 4-Dioxopyrimidine;Pyrimidine-2,4-diol;
NameUracil
CAS66-22-8
SynonymsSQ 7726;Urazil;pyrimidine-2,4(1H,3H)-dione;2,4-Pyrimidinediol;2,4-Pyrimidinedione;2,4-Dihydroxypyrimidine;4-hydroxy-2(1H)-pyrimidinone;2,4-Dihydroxypyrimidine(Uracil);BMS 205603-01;2,4(1H,3H)-Pyrimidinedione (9CI);2,4-(1H,3H)-pyrimidinedione (9CI);RU 12709;Uracil (8CI);SQ 6201;2,4(1H,3H)-pyrimidinedione;2, 4 (1H,3H)-Pyrimidinedione;2-hydroxy-4(1H)-pyrimidinone;Uracil (JAN/USAN);2,4-Dioxopyrimidine;Hybar X;Pyrod;Ura;Pirod;SQ 8493;1H-pyrimidine-2,4-dione;2, 4-Dioxopyrimidine;Pyrimidine-2,4-diol;
EINECS(EC#)200-621-9
Molecular FormulaC4H4N2O2
Molecular Weight112.09
Appearancefine off-white crystalline powder
refractive index1.501
storage tempKeep tightly closed. Keep away from heat, sparks, and open flame.
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass4.2
Hazard UN
NO.
Safety
Moderately toxic by intraperitoneal route. An experimental teratogen. Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes of Uracil (CAS NO.66-22-8):?Xi
WGK Germany:?2
Safety Statements:?22-24/25?
S22: Do not breathe dust.?
S24/25: Avoid contact with skin and eyes.
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| dog |
LD50 |
oral |
> 5gm/kg (5000mg/kg) |
? |
Medicamentos de Actualidad. Vol. 21, Pg. 125, 1985. |
| mouse |
LD50 |
intraperitoneal |
1513mg/kg (1513mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) |
Journal of Pharmacology and Experimental Therapeutics. Vol. 207, Pg. 504, 1978. |
| mouse |
LD50 |
oral |
> 8gm/kg (8000mg/kg) |
? |
Oyo Yakuri. Pharmacometrics. Vol. 20, Pg. 1009, 1980. |
| rabbit |
LD50 |
oral |
> 10gm/kg (10000mg/kg) |
? |
Medicamentos de Actualidad. Vol. 21, Pg. 125, 1985. |
| rat |
LD50 |
oral |
> 6gm/kg (6000mg/kg) |
? |
Medicamentos de Actualidad. Vol. 21, Pg. 125, 1985. |
