Methyl methanesulfonate cas no:66-27-3
Synonyms: MMS; Methanesulfonic acid methyl ester; METHYLMETHANE SULPHONATE 99%
NameMethyl methanesulfonate
CAS66-27-3
SynonymsMMS; Methanesulfonic acid methyl ester; METHYLMETHANE SULPHONATE 99%
EINECS(EC#)200-625-0
Molecular FormulaC2H6O3S
Molecular Weight110.13
Appearancecolourless liquid
refractive index1.413-1.415
storage tempKeep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Hazard T:Toxic;
Risk R22;R36/37/38;R45;R68
Safety
Confirmed carcinogen with carcinogenic and neoplastigenic data. Poison by ingestion, intraperitoneal, intravenous, and subcutaneous routes. Human mutation data reported. Experimental teratogenic and reproductive effects. When heated to decomposition it emits toxic fumes of SOx. See also SULFONATES and ESTERS.
Hazard Codes: T
Risk Statements: 45-22-36/37/38-68
R45: May cause cancer
R22: Harmful if swallowed
R36/37/38: Irritating to eyes, respiratory system and skin
R68: Possible risk of irreversible effects
Safety Statements: 53-26-45-36/37/39
S53: Avoid exposure - obtain special instruction before use
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection
RIDADR: UN 2810 6.1/PG
WGK Germany: 3
F21: Sensitive to humidity
HazardClass: 6.1(b)
PackingGroup: III
Hazardous Substances Data: 66-27-3(Hazardous Substances Data)
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| bird - wild |
LD50 |
oral |
56200ug/kg (56.2mg/kg) |
|
Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983. |
| dog |
LDLo |
intravenous |
22mg/kg (22mg/kg) |
BLOOD: LEUKOPENIA
BLOOD: OTHER CHANGES |
Cancer Chemotherapy Reports, Part 2. Vol. 2, Pg. 203, 1965. |
| mouse |
LD50 |
intraperitoneal |
180mg/kg (180mg/kg) |
|
Mutation Research. Vol. 223, Pg. 383, 1989. |
| mouse |
LD50 |
oral |
290mg/kg (290mg/kg) |
|
Mutation Research. Vol. 223, Pg. 383, 1989. |
| quail |
LD50 |
oral |
75mg/kg (75mg/kg) |
|
Journal of Reproduction and Fertility. Vol. 48, Pg. 371, 1976. |
| rat |
LD50 |
intraperitoneal |
114mg/kg (114mg/kg) |
|
Food and Chemical Toxicology. Vol. 22, Pg. 665, 1984. |
| rat |
LD50 |
intravenous |
175mg/kg (175mg/kg) |
|
Zeitschrift fuer Krebsforschung. Vol. 74, Pg. 241, 1970. |
| rat |
LD50 |
oral |
225mg/kg (225mg/kg) |
|
Food and Cosmetics Toxicology. Vol. 19, Pg. 347, 1981. |
| rat |
LD50 |
subcutaneous |
125mg/kg (125mg/kg) |
|
Zeitschrift fuer Krebsforschung. Vol. 74, Pg. 241, 1970. |
RTECS: PB2625000
