66085-59-4|NimodipineProducts Supply - Chemical intermediates Network

Nimodipine cas no:66085-59-4

Synonyms: 3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-methoxyethyl 1-methylethylester (9CI);Admon;3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-(2-methoxyethyl)5-(1-methylethyl) ester;Nimodipine AP;Nimotop;Periplum;

Identification

NameNimodipine
CAS66085-59-4
Synonyms3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-methoxyethyl 1-methylethylester (9CI);Admon;3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-(2-methoxyethyl)5-(1-methylethyl) ester;Nimodipine AP;Nimotop;Periplum;
EINECS(EC#)266-127-0
Molecular FormulaC₂₁H₂₆N₂O₇
Molecular Weight418.44034

Chemical Properties

Appearanceyellow crystalline powder
refractive index1.561
storage tempStore in a tightly closed container. Store in a dry area.

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

HazardclassIRRITANT

Safety Data

Hazard Xn:Harmful
Risk R20/21/22
Safety

Poison by intravenous route. Moderately toxic by ingestion. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NO_x.
Hazard Codes:? Harmful Xn
Risk Statements: 20/21/22?
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 36?
S36: Wear suitable protective clothing.
WGK Germany: 1
RTECS of Nimodipine (CAS NO.66085-59-4): US7975500

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intravenous	4mg/kg (4mg/kg)	?	Arzneimittel-Forschung. Drug Research. Vol. 36, Pg. 1733, 1986.
dog	LD50	oral	1gm/kg (1000mg/kg)	?	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 6899, 1985.
mouse	LD50	intravenous	26200ug/kg (26.2mg/kg)	?	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 6899, 1985.
mouse	LD50	oral	940mg/kg (940mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 6899, 1985.
mouse	LD50	subcutaneous	9500mg/kg (9500mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 6899, 1985.
rabbit	LD50	intravenous	2500ug/kg (2.5mg/kg)	?	Arzneimittel-Forschung. Drug Research. Vol. 36, Pg. 1733, 1986.
rabbit	LD50	oral	5gm/kg (5000mg/kg)	?	Arzneimittel-Forschung. Drug Research. Vol. 36, Pg. 1733, 1986.
rat	LD50	intravenous	5mg/kg (5mg/kg)	?	Archives of Toxicology. Vol. 54, Pg. 275, 1983.
rat	LD50	oral	2738mg/kg (2738mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 6899, 1985.
rat	LD50	subcutaneous	4234mg/kg (4234mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Kiso to Rinsho. Clinical Report. Vol. 19, Pg. 6899, 1985.

supplier list

Wuhan Taiyicheng Biopharmaceutical Co., Ltd.: Tel:; Address: 7#, Meijiashan, Wuchang District, Wuhan, Hubei province, China

Shandong Boyuan Chemical Co.,Ltd.: Tel:+86-531 87771418 88963280; Address: 50 Sang Yuan Road, Jinan 250100, Shandong, China

Shandong Xinhua Pharmaceutical Co.,Ltd.: Tel:0086 533 2196804 /2196811/2284360; Address: No.14,Dongyi Road,Zibo,Shandong,China

Nantong Chem-Tech.(Group) Co., Ltd.: Tel:+86-(513)-8508-1108, 8533-5860; Address: 7/F Beihao BLDG, No. 91,Zhongxiu Middle Road, Nantong 226001,

Dalian Holley Dalian Li Jin Pharmaceutical Co., Ltd.: Tel:+86-(411)-8769-0056; Address: Cheng'en Street, 8, Jinzhou District, Dalian, Liaoning 116100,

Jintan Xilin Pharmaceutical Raw Material Co. Ltd.: Tel:+86-(519)-2861296; Address: Baita Town, Northern Suburb, Jintan, Jiangsu 213200,

Kingreat Chemistry Company Limited: Tel:+86-(592)-2299609; Address: Suite E, 14/F,Jinyuan Plaza, No.57, Hubin Road (S), Xiamen 361004,

Qilong Chemical Co., Ltd.: Tel:86-574-63858500; Address: No.586, Jiangnan Road,High-tech Park, Ningbo, Zhejiang 315040,

Tocris Bioscience: Tel:+1-(800)-421-3701; Address: 16144 Westwoods Business Park, Ellisville, Missouri 63021,

Zhejiang Ouhua Chemical Imp.& Exp. Co., Ltd.: Tel:+86-(576)-888-26569; Address: No.196 Hisun Avenue, Jiaojiang, Taizhou, Zhejiang 318000,

Tecoland Corporation: Tel:+1-(732)-603-9577; Address: 100 Menlo Park Drive, Suite 316, Edison, New Jersey 08837-2428,

Facus Pharmaceutical Co., Ltd.: Tel:+86-(574)-6237-8411; Address: 24Fl, Yuanjing Building, Beilun, Ningbo, Zhejiang 315800,

Changzhou Sinly Pharmchem Co., Ltd.: Tel:+86-(519)-86608206/88121371; Address: Room 516, Luckystar, No.218,Guanghua Street, Changzhou, Jiangsu 213001,

Tianjin Hi-Tesion Bio&Chem Co., Ltd.: Tel:+86-(22)-2372-5099; Address: C1506, Wanhao Mansion, No.333 Binshuixi Road, Nankai District, Tianjin 300381,

Shanxi Ruicheng Pharma Middle Product Co., Ltd.: Tel:+86-(359)-302-4797; Address: No 1, Bayi Road, Ruicheng, Shanxi 044600,

Nimodipine cas no:66085-59-4

Directory

supplier list