66357-35-5|RanitidineProducts Supply - Chemical intermediates Network

Ranitidine cas no:66357-35-5

Synonyms: Midaven;Zenetac;1,1-Ethenediamine, N-(2-(((5-((dimethylamino)methyl)-2-furanyl)methyl)thio)ethyl)-N'-methyl-2-nitro-;Acidex;

Identification

NameRanitidine
CAS66357-35-5
SynonymsMidaven;Zenetac;1,1-Ethenediamine, N-(2-(((5-((dimethylamino)methyl)-2-furanyl)methyl)thio)ethyl)-N'-methyl-2-nitro-;Acidex;
EINECS(EC#)266-332-5
Molecular FormulaC₁₃H₂₂N₄O₃S
Molecular Weight350.87

Chemical Properties

AppearanceWhite powder
refractive index1.558
storage tempRanitidine hydrochloride tablets or solution should be stored in a dry place at 15-30C in tight, light-resistant containers.

Safety Data

Safety

Safety Statements: 22-24/25?
S22: Do not breathe dust
S24/25: Avoid contact with skin and eyes
WGK Germany: 2
RTECS: KM6557000

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
man	TDLo	oral	4286ug/kg/2D- (4.286mg/kg)	BEHAVIORAL: REGIDITY BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP	American Journal of Emergency Medicine. Vol. 17, Pg. 258, 1999.
man	TDLo	oral	60mg/kg/14D-I (60mg/kg)	LIVER: "JAUNDICE, CHOLESTATIC" LIVER: LIVER FUNCTION TESTS IMPAIRED SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	American Journal of Gastroenterology. Vol. 93, Pg. 822, 1998.
mouse	LD50	intramuscular	280mg/kg (280mg/kg)	?	United States Patent Document. Vol. #4613602,
mouse	LD50	intravenous	80mg/kg (80mg/kg)	?	United States Patent Document. Vol. #4613602,
mouse	LD50	oral	884mg/kg (884mg/kg)	?	European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 25, Pg. 749, 1990.
rat	LD50	intramuscular	2018mg/kg (2018mg/kg)	?	United States Patent Document. Vol. #4613602,
rat	LD50	intravenous	93mg/kg (93mg/kg)	?	United States Patent Document. Vol. #4613602,
rat	LD50	oral	> 5gm/kg (5000mg/kg)	?	United States Patent Document. Vol. #4613602,
women	TDLo	oral	12mg/kg/2D-I (12mg/kg)	KIDNEY, URETER, AND BLADDER: INTERSTITIAL NEPHRITIS BLOOD: OTHER CHANGES SKIN AND APPENDAGES (SKIN): "DERMATITIS, ALLERGIC: AFTER TOPICAL EXPOSURE"	American Journal of Emergency Medicine. Vol. 12, Pg. 67, 1994.

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Global ChemSources, Inc.: Tel:+1-(203)-762-9901, 973 857-1076; Address: P.O. 7422, Wilton, Connecticut 06897,

Ranitidine cas no:66357-35-5

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