665-66-7|1-Adamantanamine hydrochlorideProducts Supply

1-Adamantanamine hydrochloride cas no:665-66-7

Synonyms: 1-Aminoadamantane hydrochloride; Amantadine hydrochloride; AMANTADINE HCL; 1-Adamantamine hydrochloride 99%

Identification

Name1-Adamantanamine hydrochloride
CAS665-66-7
Synonyms1-Aminoadamantane hydrochloride; Amantadine hydrochloride; AMANTADINE HCL; 1-Adamantamine hydrochloride 99%
EINECS(EC#)211-560-2
Molecular FormulaC10H17N?HCl
Molecular Weight187.71

Chemical Properties

AppearanceCrystalline Solid
refractive index1.558
storage tempStore in a cool, dry place. Store in a tightly closed container.
Sensitive Hygroscopic

Safety Data

Hazard Xn:Harmful
Risk R22
Safety

Safety Information of Amantadine hydrochloride (CAS NO.665-66-7):
Hazard Codes: Xn Harmful
Risk Statements: 22-40-20/21/22
20:?Harmful by inhalation?
21:?Harmful in contact with skin?
22:?Harmful if swallowed?
40:?Limited evidence of a carcinogenic effect?
Safety Statements: 22-36/37-36
22:?Do not breathe dust?
36:?Wear suitable protective clothing??
37:?Wear suitable gloves?

HS Code 29213099

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intravenous	37mg/kg (37mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Toxicology and Applied Pharmacology. Vol. 15, Pg. 642, 1969.
guinea pig	LD50	oral	360mg/kg (360mg/kg)	BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Toxicology and Applied Pharmacology. Vol. 15, Pg. 642, 1969.
man	LDLo	oral	28571ug/kg (28.571mg/kg)	BEHAVIORAL: TOXIC PSYCHOSIS LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA BLOOD: HEMORRHAGE	American Journal of Psychiatry. Vol. 145, Pg. 267, 1988.
man	LDLo	oral	286mg/kg (286mg/kg)	BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" BEHAVIORAL: EXCITEMENT BEHAVIORAL: TOXIC PSYCHOSIS	American Journal of Psychiatry. Vol. 145, Pg. 267, 1988.
man	TDLo	oral	13mg/kg/5D-I (13mg/kg)	BEHAVIORAL: EUPHORIA BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS"	American Journal of Psychiatry. Vol. 143, Pg. 1170, 1985.
man	TDLo	oral	24mg/kg/1D-I (24mg/kg)	BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" BEHAVIORAL: EXCITEMENT	Annals of Emergency Medicine. Vol. 19, Pg. 668, 1990.
mouse	LD50	intraperitoneal	198mg/kg (198mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 164, 1988.
mouse	LD50	intravenous	95mg/kg (95mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 164, 1988.
mouse	LD50	oral	700mg/kg (700mg/kg)	BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Toxicology and Applied Pharmacology. Vol. 15, Pg. 642, 1969.
mouse	LD50	subcutaneous	290mg/kg (290mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 164, 1988.
rat	LD50	intraperitoneal	150mg/kg (150mg/kg)	BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Toxicology and Applied Pharmacology. Vol. 15, Pg. 642, 1969.
rat	LD50	intravenous	90mg/kg (90mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 164, 1988.
rat	LD50	oral	800mg/kg (800mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 19, Pg. 164, 1988.
rat	LD50	subcutaneous	500mg/kg (500mg/kg)	?	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 13, Pg. 1269, 1971.
women	LDLo	oral	50mg/kg (50mg/kg)	BEHAVIORAL: COMA CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP CARDIAC: PULSE RATE	American Journal of Medicine. Vol. 77, Pg. 388, 1984.

supplier list

ORICHEM INTERNATIONAL LTD.: Tel:86-0571-85270505; Address: FLAT E,16/F,1 HUAZHE PLAZA,HANGZHOU,

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Shanghai Richem International Co., Ltd.: Tel:+86-(21)-31263688; Address: Room 603, Golden Eagle Mansion A, No.1518 Minsheng Road, Pudong, Shanghai 200135,

Chemner Pharma: Tel:+86-(23)-62482345; Address: 668# International Exhibtion and Conference Center, Chongqing, Sichuan 400060,

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Haihang Industry Co., Ltd.: Tel:+86-(531)-88032799; Address: 2/F, East Tower, Bldg 12, No. 2 Qilihe Road, Jinan 250100,

Parchem - Fine & Specialty Chemicals: Tel:+1-(914)-654-6800, 800-282-3982; Address: 415 Huguenot Street, New Rochelle, New York 10801,

Advanced Technology & Industrial Co., Ltd.: Tel:(852) 23902293; Address: Unit B, 1/F., Cheong Shing Bldg., 17 Walnut St., Tai Kok Tsui, Kln,

Laiwu Hehui Chemical Co.,Ltd.: Tel:+86-(531)-88772589; Address: Huashan Rd., Jinan City, Shandong 250000,

Wujiang Yingchuang Chemical Co., Ltd.: Tel:+86-(25)-8645 8768; Address: 215 Ying Tian Da Street, JianYe, Nanjing, Jiangsu 210017,

1-Adamantanamine hydrochloride cas no:665-66-7

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