Colforsin cas no:66575-29-9
Synonyms: 1H-Naphtho[2,1-b]pyran-1-one,5-(acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-,[3R-(3a,4ab,5b,6b,6aa,10a,10ab,10ba)]-;(-)-Forskolin;Coleonol;ForsLean;HL 362;NSC 357088;NSC 375489;
NameColforsin
CAS66575-29-9
Synonyms1H-Naphtho[2,1-b]pyran-1-one,5-(acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-,[3R-(3a,4ab,5b,6b,6aa,10a,10ab,10ba)]-;(-)-Forskolin;Coleonol;ForsLean;HL 362;NSC 357088;NSC 375489;
EINECS(EC#)266-410-9
Molecular FormulaC22H34O7
Molecular Weight410.50116
AppearanceColorless Crystalline Solid
refractive index1.551
storage temp−20°C
Hazard Xn: Harmful;
Risk R21
Safety
Hazard Codes: 
Xn
Risk Statements: 21
R21: Harmful in contact with skin.
Safety Statements: 22-36/37
S22: Do not breathe dust.
S36/37: Wear suitable protective clothing and gloves.
WGK Germany :3
RTECS: QL6150000
F: 10-21
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intraperitoneal |
68mg/kg (68mg/kg) |
BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) |
Journal of Ethnopharmacology. Vol. 3, Pg. 1, 1981. |
| mouse |
LD50 |
oral |
3100mg/kg (3100mg/kg) |
|
Medicinal Research Reviews. Vol. 3, Pg. 201, 1983. |
| rat |
LD50 |
intraperitoneal |
92mg/kg (92mg/kg) |
|
Journal of Medicinal Chemistry. Vol. 31, Pg. 1872, 1988. |
| rat |
LD50 |
oral |
2550mg/kg (2550mg/kg) |
|
Medicinal Research Reviews. Vol. 3, Pg. 201, 1983. |
