Yohimban-16-carboxylicacid, 17-hydroxy-, methyl ester, monohydrochloride, (16b,17a)- (9CI) cas no:66634-44-4

NameYohimban-16-carboxylicacid, 17-hydroxy-, methyl ester, monohydrochloride, (16b,17a)- (9CI)
CAS66634-44-4
SynonymsBenz[g]indolo[2,3-a]quinolizine,yohimban-16-carboxylic acid deriv.; Corynanthine hydrochloride
EINECS(EC#)266-430-8
Molecular FormulaC21H26 N2 O3 . Cl H
Molecular Weight 390.90

storage temp2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :

ZG1025000

CHEMICAL NAME :

Yohimban-16-beta-carboxylic acid, 17-alpha-hydroxy-, methyl ester, hydrochloride

CAS REGISTRY NUMBER :

66634-44-4

LAST UPDATED :

199706

DATA ITEMS CITED :

2

MOLECULAR FORMULA :

C21-H26-N2-O3.Cl-H

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

75 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 50,241,1935

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - guinea pig

DOSE/DURATION :

158 mg/kg

TOXIC EFFECTS :

Behavioral - altered sleep time (including change in righting reflex) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

REFERENCE :

CRSBAW Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1849- Volume(issue)/page/year: 146,1042,1952