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Choline chloride cas no:67-48-1

Synonyms: Choline hydrochloride;Choline chloride solutions;(2-Hydroxyethyl)trimethylammonium chloride;Cholinum;Ethanaminium, 2-hydroxy-N,N, N-trimethyl-, chloride;Hormocline;Colina cloruro [DCIT];2-Hydroxy-N,N,N-trimethylethanaminium chloride;Ammonium, (2-hydroxyethyl)trimethyl-, chloride;2-Hydroxy-N,N,N-trimethylethanaminium;Cholinium chloride;sell choline chloride;Bilineurin chloride;Ethanaminium, 2-hydroxy-N,N,N-trimethyl-;Paresan;2-hydroxyethyl-trimethyl-azanium;Neocolina;Choline chlorhydrate;Lipotril;2-Hydroxy-N,N,N-trimethylammonium chloride;Choline, chloride;Chloride de choline [French];Chlorure de choline [INN-French];Biocolina;Cholini chloridum [INN-Latin];2-hydroxyethyl-trimethyl-azanium chloride;

Identification
NameCholine chloride
CAS67-48-1
SynonymsCholine hydrochloride;Choline chloride solutions;(2-Hydroxyethyl)trimethylammonium chloride;Cholinum;Ethanaminium, 2-hydroxy-N,N, N-trimethyl-, chloride;Hormocline;Colina cloruro [DCIT];2-Hydroxy-N,N,N-trimethylethanaminium chloride;Ammonium, (2-hydroxyethyl)trimethyl-, chloride;2-Hydroxy-N,N,N-trimethylethanaminium;Cholinium chloride;sell choline chloride;Bilineurin chloride;Ethanaminium, 2-hydroxy-N,N,N-trimethyl-;Paresan;2-hydroxyethyl-trimethyl-azanium;Neocolina;Choline chlorhydrate;Lipotril;2-Hydroxy-N,N,N-trimethylammonium chloride;Choline, chloride;Chloride de choline [French];Chlorure de choline [INN-French];Biocolina;Cholini chloridum [INN-Latin];2-hydroxyethyl-trimethyl-azanium chloride;
EINECS(EC#)200-655-4
Molecular FormulaC5H14ClNO
Molecular Weight139.62
Chemical Properties
AppearanceWhite crystalline powder
storage temp0-6°C
Sensitive Hygroscopic
Safety Data

Hazard Xi:Irritant
Risk R36/37/38
Safety

Hazard Codes:? Xi
The Risk Statements information of? Choline chloride :
36/37/38:? Irritating to eyes, respiratory system and skin?
The Safety Statements information of? Choline chloride :
26:? In case of contact with eyes, rinse immediately with plenty of WATER and seek medical advice?
36:? Wear suitable protective clothing?
WGK Germany: 1
RTECS: KH2975000
F: 3-9


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo intravenous 25mg/kg (25mg/kg) ? "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
dog LDLo intravenous 5mg/kg (5mg/kg) ? "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
frog LDLo unreported 1500mg/kg (1500mg/kg) ? Proceedings of the Society for Experimental Biology and Medicine. Vol. 51, Pg. 281, 1942.
mouse LD50 intraperitoneal 320mg/kg (320mg/kg) ? Proceedings of the Society for Experimental Biology and Medicine. Vol. 51, Pg. 281, 1942.
mouse LD50 intravenous 53mg/kg (53mg/kg) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Arzneimittel-Forschung. Drug Research. Vol. 33, Pg. 1016, 1983.
mouse LD50 oral 3900mg/kg (3900mg/kg) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Arzneimittel-Forschung. Drug Research. Vol. 33, Pg. 1016, 1983.
mouse LDLo subcutaneous 735mg/kg (735mg/kg) ? Journal of Pharmacology and Experimental Therapeutics. Vol. 6, Pg. 477, 1914/1915.
rabbit LDLo intraperitoneal 500mg/kg (500mg/kg) SENSE ORGANS AND SPECIAL SENSES: CORNEAL DAMAGE: EYE

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of Infectious Diseases. Vol. 42, Pg. 473, 1928.
rabbit LDLo intravenous 1100ug/kg (1.1mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: CYANOSIS

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Proceedings of the Society for Experimental Biology and Medicine. Vol. 51, Pg. 281, 1942.
rabbit LDLo rectal 1gm/kg (1000mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: CYANOSIS

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Proceedings of the Society for Experimental Biology and Medicine. Vol. 51, Pg. 281, 1942.
rabbit LDLo subcutaneous 1gm/kg (1000mg/kg) ? Proceedings of the Society for Experimental Biology and Medicine. Vol. 51, Pg. 281, 1942.
rat LD50 intraperitoneal 450mg/kg (450mg/kg) ? Indian Journal of Experimental Biology. Vol. 24, Pg. 91, 1986.
rat LD50 oral 3400mg/kg (3400mg/kg) SENSE ORGANS AND SPECIAL SENSES: CHROMODACYRORREA: EYE

BEHAVIORAL: EXCITEMENT

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Proceedings of the Society for Experimental Biology and Medicine. Vol. 58, Pg. 87, 1945.

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