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Methyl sulfoxide cas no:67-68-5

Synonyms: Dimethyl sulfoxide, USP Grade DMSO, USP Grade; DMSO~Methyl sulphoxide; methyl sulfoxide B&J brand 1 L; methyl sulfoxide absolute over molecular sieve (H2O <0.01%); dimethyl sulfoxide hybri-max sterile*filtered; dimethyl sulfoxide plant cell culture*tested; Dimethyl sulfoxide, sterile filtered DMSO, sterile filtered; Diemthyl Sulfoxide; Dimethyl Sulfoxide BP; Dimethyl sulphoxide; DMSO/NMP (Dimethylsulfoxide/1-Methyl-2-pyrrolidone); DMSO; Dimethyl sulfoxide; Dimethylsulfoxide Sulfinylbis;

Identification
NameMethyl sulfoxide
CAS67-68-5
SynonymsDimethyl sulfoxide, USP Grade DMSO, USP Grade; DMSO~Methyl sulphoxide; methyl sulfoxide B&J brand 1 L; methyl sulfoxide absolute over molecular sieve (H2O <0.01%); dimethyl sulfoxide hybri-max sterile*filtered; dimethyl sulfoxide plant cell culture*tested; Dimethyl sulfoxide, sterile filtered DMSO, sterile filtered; Diemthyl Sulfoxide; Dimethyl Sulfoxide BP; Dimethyl sulphoxide; DMSO/NMP (Dimethylsulfoxide/1-Methyl-2-pyrrolidone); DMSO; Dimethyl sulfoxide; Dimethylsulfoxide Sulfinylbis;
EINECS(EC#)200-664-3
Molecular FormulaC2H6OS
Molecular Weight78.12
Chemical Properties
Appearancecolorless liquid
refractive index1.477-1.48
storage tempStore at RT.
Sensitive Hygroscopic
Safety Data

Hazard Xi:Irritant
Risk R36/37/38
Safety

Hazard Codes of Dimethyl sulfoxide (CAS NO.67-68-5):?Xi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 24/25-37/39-26-36-23
S24/25:Avoid contact with skin and eyes.?
S37/39:Wear suitable gloves and eye/face protection.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36:Wear suitable protective clothing.?
S23:Do not breathe vapour.
WGK Germany: 1
RTECS: PV6210000
F: 3
HS Code: 29309070


HS Code 29309070

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
bird - wild LD50 oral 100mg/kg (100mg/kg) ? Toxicology and Applied Pharmacology. Vol. 21, Pg. 315, 1972.
cat LDLo intravenous 200mg/kg (200mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) Arzneimittel-Forschung. Drug Research. Vol. 28, Pg. 1571, 1978.
chicken LD50 oral 12gm/kg (12000mg/kg) ? Journal of Pharmacy and Pharmacology. Vol. 15, Pg. 688, 1963.
dog LD50 intravenous 2500mg/kg (2500mg/kg) CARDIAC: OTHER CHANGES

KIDNEY, URETER, AND BLADDER: HEMATURIA

KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Cancer Chemotherapy Reports. Vol. 31, Pg. 7, 1963.
dog LD50 oral > 10gm/kg (10000mg/kg) ? Annals of the New York Academy of Sciences. Vol. 141, Pg. 96, 1967.
guinea pig LDLo intraperitoneal > 5500mg/kg (5500mg/kg) ? Journal of Pharmacy and Pharmacology. Vol. 15, Pg. 688, 1963.
guinea pig LDLo oral > 11gm/kg (11000mg/kg) ? Journal of Pharmacy and Pharmacology. Vol. 15, Pg. 688, 1963.
mammal (species unspecified) LD50 oral 21400mg/kg (21400mg/kg) ? Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 39(4), Pg. 86, 1974.
man TDLo intravenous 606mg/kg (606mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING

LIVER: "JAUNDICE, OTHER OR UNCLASSIFIED"
Lancet. Vol. 2, Pg. 1004, 1980.
mouse LD50 intraperitoneal 2500mg/kg (2500mg/kg) ? Russian Pharmacology and Toxicology Vol. 35, Pg. 300, 1972.
mouse LD50 intravenous 3100mg/kg (3100mg/kg) SENSE ORGANS AND SPECIAL SENSES: HEMORRHAGE: EYE

SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE
Toxicology and Applied Pharmacology. Vol. 15, Pg. 74, 1969.
mouse LD50 oral 7920mg/kg (7920mg/kg) ? Chimica Therapeutica. Vol. 3, Pg. 10, 1968.
mouse LD50 skin 50gm/kg (50000mg/kg) ? Annals of the New York Academy of Sciences. Vol. 141, Pg. 96, 1967.
mouse LD50 subcutaneous 14gm/kg (14000mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

KIDNEY, URETER, AND BLADDER: HEMATURIA
Annals of the New York Academy of Sciences. Vol. 141, Pg. 96, 1967.
mouse LD50 unreported 12gm/kg (12000mg/kg) ? United States Patent Document. Vol. #4767763,
rat LD50 intraperitoneal 8200mg/kg (8200mg/kg) ? Food and Chemical Toxicology. Vol. 22, Pg. 665, 1984.
rat LD50 intravenous 5360mg/kg (5360mg/kg) BEHAVIORAL: TREMOR

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: MUSCLE WEAKNESS
Toxicology and Applied Pharmacology. Vol. 7, Pg. 104, 1965.
rat LD50 oral 14500mg/kg (14500mg/kg) SENSE ORGANS AND SPECIAL SENSES: HEMORRHAGE: EYE

SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE
Toxicology and Applied Pharmacology. Vol. 15, Pg. 74, 1969.
rat LD50 skin 40gm/kg (40000mg/kg) ? Annals of the New York Academy of Sciences. Vol. 141, Pg. 96, 1967.
rat LD50 subcutaneous 12gm/kg (12000mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Arzneimittel-Forschung. Drug Research. Vol. 14, Pg. 1050, 1964.
rat LD50 unreported 1300mg/kg (1300mg/kg) ? National Technical Information Service. Vol. AD-A159-418,
women TDLo skin 1800mg/kg (1800mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

LUNGS, THORAX, OR RESPIRATION: CYANOSIS

BLOOD: OTHER CHANGES
Veterinary and Human Toxicology. Vol. 40, Pg. 87, 1998.

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