hexachloroethane cas no:67-72-1
Synonyms: 1,1,1,2,2,2-hexachloroethane; avlothane; distokal; distopan; distopin; carbon hexachloride; egitol; ethane hexachloride; ethylene hexachloride; falkitol; fasciolin; HCE; mottenhexe; perchloroethane; phenohep
Namehexachloroethane
CAS67-72-1
Synonyms1,1,1,2,2,2-hexachloroethane; avlothane; distokal; distopan; distopin; carbon hexachloride; egitol; ethane hexachloride; ethylene hexachloride; falkitol; fasciolin; HCE; mottenhexe; perchloroethane; phenohep
EINECS(EC#)200-666-4
Molecular FormulaC2Cl6
Molecular Weight236.74
Appearancewhite crystalline powder
refractive index1.533
storage temp2-8°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass9
Hazard Xn:Harmful
Risk R36/37/38;R40;R51/53
Safety
Confirmed carcinogen with experimental carcinogenic data. A poison by intravenous route. Moderately toxic by intraperitoneal route. Mildly toxic by ingestion. Experimental reproductive effects. Mutation data reported. Liver injury has resulted from exposure to this material. An insecticide. Slightly explosive by spontaneous chemical reaction. Dehalogenation of this material by reaction with alkalies, metals, etc., will produce spontaneously explosive chloroacetylenes. When heated to decomposition it emits highly toxic fumes of Cl? and phosgene.?
Hazard Codes:?Xn,?N,?T,?F
Risk Statements: 40-51/53-36/37/38-39/23/24/25-36/38-23/24/25-11?
R40:Limited evidence of a carcinogenic effect.?
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.?
R36/37/38:Irritating to eyes, respiratory system and skin.?
R39/23/24/25:Danger of very serious irreversible effects and Toxic by inhalation, in contact with skin and if swallowed.?
R36/38:Irritating to eyes and skin.?
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.?
R12:Extremely flammable.
Safety Statements: 36/37-61-45-36/37/39-26-24-16-7?
S36/37:Wear suitable protective clothing and gloves.?
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S24:Avoid contact with skin.?
S16:Keep away from sources of ignition.?
S7:Keep container tightly closed.
RIDADR: UN 9037
WGK Germany: 3
RTECS: KI4025000
HazardClass: 9
PackingGroup: III
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| dog |
LDLo |
intravenous |
325mg/kg (325mg/kg) |
? |
Quarterly Journal of Pharmacy & Pharmacology. Vol. 7, Pg. 205, 1934. |
| guinea pig |
LD50 |
oral |
4970mg/kg (4970mg/kg) |
? |
American Industrial Hygiene Association Journal. Vol. 40, Pg. 187, 1979. |
| mouse |
LD50 |
intraperitoneal |
4500mg/kg (4500mg/kg) |
? |
Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 902, 1961. |
| rabbit |
LD |
oral |
> 1gm/kg (1000mg/kg) |
? |
American Industrial Hygiene Association Journal. Vol. 40, Pg. 187, 1979. |
| rabbit |
LD50 |
skin |
32gm/kg (32000mg/kg) |
? |
American Industrial Hygiene Association Journal. Vol. 40, Pg. 187, 1979. |
| rabbit |
LDLo |
subcutaneous |
4gm/kg (4000mg/kg) |
? |
Quarterly Journal of Pharmacy & Pharmacology. Vol. 7, Pg. 205, 1934. |
| rat |
LCLo |
inhalation |
5900ppm/8H (5900ppm) |
BEHAVIORAL: MUSCLE WEAKNESS |
American Industrial Hygiene Association Journal. Vol. 40, Pg. 187, 1979. |
| rat |
LD50 |
oral |
4460mg/kg (4460mg/kg) |
? |
American Industrial Hygiene Association Journal. Vol. 40, Pg. 187, 1979. |
| rat |
LDLo |
intraperitoneal |
2900mg/kg (2900mg/kg) |
? |
American Industrial Hygiene Association Journal. Vol. 40, Pg. 187, 1979. |
?
