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Atumin cas no:67-92-5

Synonyms: [1,1'-Bicyclohexyl]-1-carboxylicacid, 2-(diethylamino)ethyl ester, hydrochloride (9CI);[Bicyclohexyl]-1-carboxylic acid, 2-(diethylamino)ethyl ester hydrochloride(6CI,7CI,8CI); Atumin; Benacol; Bentomine; Bentyl hydrochloride; Di-Syntramine;Dicyclomine hydrochloride; Dicycloverin hydrochloride; Diocyl hydrochloride;Dyspas; Mamiesan; Merbentyl; Procyclomin; Wyovin hydrochloride; b-Diethylaminoethyl1-cyclohexylcyclohexanecarboxylate hydrochloride

Identification
NameAtumin
CAS67-92-5
Synonyms[1,1'-Bicyclohexyl]-1-carboxylicacid, 2-(diethylamino)ethyl ester, hydrochloride (9CI);[Bicyclohexyl]-1-carboxylic acid, 2-(diethylamino)ethyl ester hydrochloride(6CI,7CI,8CI); Atumin; Benacol; Bentomine; Bentyl hydrochloride; Di-Syntramine;Dicyclomine hydrochloride; Dicycloverin hydrochloride; Diocyl hydrochloride;Dyspas; Mamiesan; Merbentyl; Procyclomin; Wyovin hydrochloride; b-Diethylaminoethyl1-cyclohexylcyclohexanecarboxylate hydrochloride
EINECS(EC#)200-671-1
Molecular FormulaC19H35 N O2 . Cl H
Molecular Weight345.95
Chemical Properties
storage temp-20°C Freezer
Safety Data

Hazard Xn
Risk 22-36/37/38
Safety

Poison by intravenous route. Moderately toxic by ingestion. Human systemic effects by ingestion: rigidity, dyspnea, cyanosis. When heated to decomposition it emits very toxic fumes of HCl and NOx.
Hazard Codes: HarmfulXn 
Risk Statements: 22-36/37/38 
R22: Harmful if swallowed. 
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36: Wear suitable protective clothing.
WGK Germany: 3
RTECS: DT7350000


Toxicity

1.    

orl-inf TDLo:1 g/kg:BAH,PUL

    BMJOAE    British Medical Journal. 288 (1984),901.
2.    

orl-rat LD50:1290 mg/kg

    DRUGAY    Drugs. International Journal of Current Therapeutics and Applied Pharmacology Reviews. 6 (1982),317.
3.    

orl-mus LD50:625 mg/kg

    JAPMA8    Journal of the American Pharmaceutical Association, Scientific Edition. 39 (1950),305.
4.    

ivn-rbt LD50:35 mg/kg

    JAPMA8    Journal of the American Pharmaceutical Association, Scientific Edition. 39 (1950),305.

supplier list

INFA S.P.A.
Tel:+39-02-777281
Address: Via Salvini 10, 20122 Milan (Italy)
THYKN (INDIA) INTERNATIONAL
Tel:+91-22-67033666 (3 lines)
Address: 202, Kuntal, Mody Estate, Nr.Pipeline, LBS Road, Ghatkopar (West), Mumbai - 400086, India
Apex Drug House
Tel:+91-22-22077266
Address: 28, Mahendra Mansion, Babu Genu Road,Mumbai-400 002.
KOA SHOJI CO., LTD.
Tel:+81-45-540-6985
Address: 17-5, Minowa-cho, 2-chome, Kohoku-ku, Yokohama-shi, Kanagawa, 223-0051, Japan
Bulk Pharmaceuticals Inc.
Tel:+1 416 321-3551
Address: 445 Milner Ave., Unit #1 Scarborough, ON Canada
Penam Pharmaceuticals Pvt. Ltd.
Tel:+91-(135)-2738083
Address: 15, Krishna Vihar, Jakhan, Rajpur Road, Dehra Dun, Uttarakhand 248001,
Parchem - Fine & Specialty Chemicals
Tel:+1-(914)-654-6800, 800-282-3982
Address: 415 Huguenot Street, New Rochelle, New York 10801,
Hui Chem Company Limited
Tel:86-21-60542966
Address: Lane 299 Bisheng Rd,Pudong District
Espee PharmaChem Pvt. Ltd.
Tel:+91-(79)-26430318/26431236
Address: 8th Floor, Devpath, off CG Road, Ahmedabad, Gujarat 380 006,
Dynamic Lifecare Pvt Ltd.
Tel:+91-(79)-29097471
Address: SF 4, Shakti Square Complex, Opp: Management Enclave, Nr. Hanumanji Temple, Vastrapur, Ahmedabad, Gujarat 380015,
Gyma Laboratories Of America, Inc.
Tel:+1-516-933-0900
Address: 135 Cantiague Rock Rd.Westbury, NY 11590
Zhejiang Kaili Industrial Co., Ltd.
Tel:86-571-85241926
Address: Block C&D,12/F,Lantian Business Center,No.18 Moganshan Road,Hangzhou,China

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