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Guanidine, N-nitroso- cas no:674-81-7

Synonyms: Guanidine,nitroso- (6CI,7CI,8CI,9CI); N-Nitrosoguanidine; NSC 33670; Nitrosoguanidine

Identification
NameGuanidine, N-nitroso-
CAS674-81-7
SynonymsGuanidine,nitroso- (6CI,7CI,8CI,9CI); N-Nitrosoguanidine; NSC 33670; Nitrosoguanidine
EINECS(EC#)200-730-1
Molecular FormulaCH4 N4 O
Molecular Weight88.09
Chemical Properties
refractive index1.665
Safety Data

Hazard Severe explosion risk.
Risk 11-20/21/22-36/37/38
Safety

Poison by intraperitoneal route. Many N-nitroso compounds are carcinogens. An explosive. Dangerous when stored in sealed containers as it decomposes to release nitrogen. When heated to decomposition it emits toxic fumes of NOx. See also N-NITROSO COMPOUNDS and EXPLOSIVES, HIGH.
Safety Information of Nitrosoguanidine (CAS NO.674-81-7):
Risk Statements: 11-20/21/22-36/37/38 
11:  Highly Flammable
20:  Harmful by inhalation 
21:  Harmful in contact with skin 
22:  Harmful if swallowed 
36:  Irritating to the eyes 
37:  Irritating to the respiratory system 
38:  Irritating to the skin 
Safety Statements: 16-26-36/37/39
16:  Keep away from sources of ignition - No smoking 
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 
36:  Wear suitable protective clothing  
37:  Wear suitable gloves   
39:  Wear eye/face protection
RIDADR: 1325


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD oral > 5gm/kg (5000mg/kg)   Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 12, Pg. 563, 1993.
mouse LDLo intraperitoneal 21mg/kg (21mg/kg)   Toxicology and Applied Pharmacology. Vol. 23, Pg. 288, 1972.
rabbit LD skin > 2gm/kg (2000mg/kg)   Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 12, Pg. 563, 1993.
rat LD oral > 5gm/kg (5000mg/kg) BEHAVIORAL: ATAXIA

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

KIDNEY, URETER, AND BLADDER: OTHER CHANGES IN URINE COMPOSITION
Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 12, Pg. 563, 1993.

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