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2-Piperidone cas no:675-20-7

Synonyms: 2-Piperidone(8CI);2-Oxopiperidine;5-Pentanolactam;Delta-valerolactam;Pentanoic acid, 5-amino-, lactam;Valerolactim;a-Piperidone;d-Valerolactam;Piperidin-2-one;

Identification
Name2-Piperidone
CAS675-20-7
Synonyms2-Piperidone(8CI);2-Oxopiperidine;5-Pentanolactam;Delta-valerolactam;Pentanoic acid, 5-amino-, lactam;Valerolactim;a-Piperidone;d-Valerolactam;Piperidin-2-one;
EINECS(EC#)211-622-9
Molecular FormulaC5H9NO
Molecular Weight99.13
Chemical Properties
Appearancewhite to yellowish low melting crystalline mass
refractive index1.448
storage tempKeep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.
Sensitive Hygroscopic
Safety Data

Hazard Xi:Irritant;
Risk R36/37
Safety

Moderately toxic by subcutaneous and intravenous routes. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes: IrritantXi
Risk Statements: 36/37-36/37/38
R36/37:Irritating to eyes and respiratory system. 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 22-24/25-37/39-26-36
S22:Do not breathe dust. 
S24/25:Avoid contact with skin and eyes. 
S37/39:Wear suitable gloves and eye/face protection. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing.
WGK Germany: 3
F: 3-10
HS Code: 29337900


HS Code 29337900

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
frog LDLo subcutaneous 3gm/kg (3000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

CARDIAC: OTHER CHANGES
Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 50, Pg. 199, 1903.
mouse LD50 intraperitoneal > 1gm/kg (1000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Journal of Pharmaceutical Sciences. Vol. 60, Pg. 1058, 1971.
mouse LD50 intravenous 600mg/kg (600mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 93, Pg. 143, 1953.
rat LD50 intravenous > 3gm/kg (3000mg/kg)   United States Patent Document. Vol. #3380887,
rat LDLo oral 11gm/kg (11000mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: CYANOSIS
National Technical Information Service. Vol. OTS0571235,

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Guangzhou Topwork Chemical Co., Ltd.
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Goly Chemical Co., Ltd.
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Shanghai Chemical Pharm-Intermediate Tech.Co., Ltd.
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Lanzhou Fast Fine Chemical Co., Ltd.
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PFALTZ-BAUER
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Syntechem Co.,Ltd
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Watson International Trading Co.,Ltd.
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Win-Win chemical Co.Ltd
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China Huanyu Chemical Industrial Co.,Ltd
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Angene International Limited
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Ningbo Inno Pharmchem Co., Ltd.
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Shanghai Forever Synthesis Co.,Ltd.
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Address: Nianjiabang Rd, Pudong, Shanghai

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