Azuleno[6,5-b]furan-2,5-dione,3,3a,4,4a,7a,8,9,9a-octahydro-4-hydroxy-4a,8-dimethyl-3-methylene-,(3aS,4S,4aR,7aR,8R,9aR)- cas no:6754-13-8

NameAzuleno[6,5-b]furan-2,5-dione,3,3a,4,4a,7a,8,9,9a-octahydro-4-hydroxy-4a,8-dimethyl-3-methylene-,(3aS,4S,4aR,7aR,8R,9aR)-
CAS6754-13-8
SynonymsAmbrosa-2,11(13)-dien-12-oicacid, 6a,8b-dihydroxy-4-oxo-, 12,8-lactone (8CI);Azuleno[6,5-b]furan-2,5-dione,3,3a,4,4a,7a,8,9,9a-octahydro-4-hydroxy-4a,8-dimethyl-3-methylene-, [3aS-(3aa,4a,4ab,7aa,8a,9aa)]-; Helenalin (6CI,7CI); (-)-Helenalin; Helenalin A; NSC 85236
Molecular FormulaC15H18 O4
Molecular Weight262.33

refractive index1.565

Hazardclass6.1(b)

Safety

RIDADR:2811
HazardClass: 6.1(b)
PackingGroup: III
Poison by ingestion and intraperitoneal routes. Mutation data reported. Human Toxicity (Merck): Intensely poisonous, capable of causing paralysis of voluntary and cardiac musculature and fatal gastroenteritis.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
domestic animals - goat/sheep	LD50	oral	100mg/kg (100mg/kg)		Pharmazie in Unserer Zeit. Vol. 10, Pg. 1, 1981.
hamster	LD50	oral	85mg/kg (85mg/kg)		Pharmazie in Unserer Zeit. Vol. 10, Pg. 1, 1981.
mouse	LD50	intraperitoneal	10mg/kg (10mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: FOOD INTAKE (ANIMAL) GASTROINTESTINAL: PERITONITIS	Research Communications in Chemical Pathology and Pharmacology. Vol. 28, Pg. 189, 1980.
mouse	LD50	oral	150mg/kg (150mg/kg)		American Journal of Veterinary Research. Vol. 37, Pg. 859, 1976.
rabbit	LD50	oral	90mg/kg (90mg/kg)		Pharmazie in Unserer Zeit. Vol. 10, Pg. 1, 1981.
rat	LD50	oral	125mg/kg (125mg/kg)		Pharmazie in Unserer Zeit. Vol. 10, Pg. 1, 1981.