68-12-2|N,N-DimethylformamideProducts Supply - Chemical intermediates Network

N,N-Dimethylformamide cas no:68-12-2

Synonyms: DMF;DMF(amide);DMFA;Dimethylformamide;N,N-Dimethylformaldehyde;Formamide,N,N-dimethyl-;N,N-Dimethylmethanamide;N-Formyldimethylamine;NSC5356;Virodene-P 058;

Identification

NameN,N-Dimethylformamide
CAS68-12-2
SynonymsDMF;DMF(amide);DMFA;Dimethylformamide;N,N-Dimethylformaldehyde;Formamide,N,N-dimethyl-;N,N-Dimethylmethanamide;N-Formyldimethylamine;NSC5356;Virodene-P 058;
EINECS(EC#)200-679-5
Molecular FormulaC₃H₇NO
Molecular Weight73.0938

Chemical Properties

AppearanceClear colorless liquid
alpha0.94 o
refractive index1.429-1.432
storage tempStore at RT.
Sensitive Hygroscopic

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass3

Safety Data

Hazard T:Toxic
Risk R20/21;R36;R61
Safety

Hazard Codes:?T
Risk Statements: 61-20/21-36?
R61:May cause harm to the unborn child.?
R20/21:Harmful by inhalation and in contact with skin.?
R36:Irritating to eyes.
Safety Statements: 53-45
S53:Avoid exposure - obtain special instructions before use.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 2265 3/PG 3
WGK Germany: 1
RTECS: LQ2100000
F: 3-10
Hazard Note: Toxic
HazardClass: 3
PackingGroup: III

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LD50	intraperitoneal	500mg/kg (500mg/kg)	LIVER: OTHER CHANGES KIDNEY, URETER, AND BLADDER: OTHER CHANGES IN URINE COMPOSITION BLOOD: CHANGES IN CELL COUNT (UNSPECIFIED)	British Journal of Industrial Medicine. Vol. 13, Pg. 51, 1956.
dog	LD50	intravenous	470mg/kg (470mg/kg)	?	Arzneimittel-Forschung. Drug Research. Vol. 15, Pg. 618, 1965.
guinea pig	LD50	intravenous	1050mg/kg (1050mg/kg)	?	Arzneimittel-Forschung. Drug Research. Vol. 15, Pg. 618, 1965.
guinea pig	LDLo	intraperitoneal	4gm/kg (4000mg/kg)	LIVER: FATTY LIVER DEGERATION	American Industrial Hygiene Association Journal. Vol. 35, Pg. 21, 1974.
mouse	LC50	inhalation	9400mg/m3/2H (9400mg/m3)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 1, Pg. 54, 1961.
mouse	LD50	intramuscular	3900mg/kg (3900mg/kg)	?	Arzneimittel-Forschung. Drug Research. Vol. 15, Pg. 618, 1965.
mouse	LD50	intraperitoneal	650mg/kg (650mg/kg)	?	Cancer Chemotherapy Reports. Vol. 30, Pg. 9, 1963.
mouse	LD50	intravenous	2500mg/kg (2500mg/kg)	?	Arzneimittel-Forschung. Drug Research. Vol. 15, Pg. 618, 1965.
mouse	LD50	oral	2900mg/kg (2900mg/kg)	?	National Technical Information Service. Vol. OTS0521148,
mouse	LD50	subcutaneous	4500mg/kg (4500mg/kg)	?	Arzneimittel-Forschung. Drug Research. Vol. 15, Pg. 618, 1965.
rabbit	LD50	intraperitoneal	1gm/kg (1000mg/kg)	LIVER: OTHER CHANGES BLOOD: CHANGES IN CELL COUNT (UNSPECIFIED) KIDNEY, URETER, AND BLADDER: OTHER CHANGES IN URINE COMPOSITION	British Journal of Industrial Medicine. Vol. 13, Pg. 51, 1956.
rabbit	LD50	intravenous	1800mg/kg (1800mg/kg)	?	Arzneimittel-Forschung. Drug Research. Vol. 15, Pg. 618, 1965.
rabbit	LD50	oral	5gm/kg (5000mg/kg)	?	National Technical Information Service. Vol. OTS0520699,
rabbit	LD50	skin	4720mg/kg (4720mg/kg)	?	American Industrial Hygiene Association Journal. Vol. 30, Pg. 470, 1969.
rat	LCLo	inhalation	5000ppm/6H (5000ppm)	?	United States Patent Document. Vol. #5122301,
rat	LD	skin	> 3160mg/kg (3160mg/kg)	?	National Technical Information Service. Vol. OTS0516779,
rat	LD50	intraperitoneal	1400mg/kg (1400mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS	British Journal of Industrial Medicine. Vol. 13, Pg. 51, 1956.
rat	LD50	intravenous	2gm/kg (2000mg/kg)	?	Zeitschrift fuer Krebsforschung. Vol. 69, Pg. 103, 1967.
rat	LD50	oral	2800mg/kg (2800mg/kg)	?	Zeitschrift fuer Krebsforschung. Vol. 69, Pg. 103, 1967.
rat	LD50	subcutaneous	3800mg/kg (3800mg/kg)	?	Arzneimittel-Forschung. Drug Research. Vol. 15, Pg. 618, 1965.
rat	LD50	unreported	> 3gm/kg (3000mg/kg)	?	Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 645, 1968.

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N,N-Dimethylformamide cas no:68-12-2

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