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19-Norpregn-5(10)-en-20-yn-3-one,17-hydroxy-, (17a)- cas no:68-23-5

Synonyms: 19-Nor-17a-pregn-5(10)-en-20-yn-3-one,17-hydroxy- (6CI,8CI); 13-Methyl-17-ethynyl-17-hydroxy-1,2,3,4,6,7,8,9,11,12,13,14,16,17-tetradecahydro-15H-cyclopenta[a]phenanthren-3-one;17-Hydroxy-19-nor-17a-pregn-5(10)-en-20-yn-3-one; 17a-Ethinyl-17b-hydroxy-D5(10)-estren-3-one; 17a-Ethynyl-17-hydroxy-5(10)-estren-3-one; 17a-Ethynyl-17b-hydroxy-5(10)-estrene-3-one; 17a-Ethynyl-17b-hydroxy-D5(10)-estren-3-one; 17a-Ethynylestr-5(10)-ene-17b-ol-3-one; 17a-Ethynylestra-5(10)-ene-17b-ol-3-one; 17b-Hydroxy-19-nor-17a-pregn-5(10)-en-20-yn-3-one;3-Oxo-17b-hydroxy-17a-ethynyl-5(10)-estrene; Enidrel;NSC 15432; Norethinodrel; Norethynodrel; Noretynodrel; SC 4642

Identification
Name19-Norpregn-5(10)-en-20-yn-3-one,17-hydroxy-, (17a)-
CAS68-23-5
Synonyms19-Nor-17a-pregn-5(10)-en-20-yn-3-one,17-hydroxy- (6CI,8CI); 13-Methyl-17-ethynyl-17-hydroxy-1,2,3,4,6,7,8,9,11,12,13,14,16,17-tetradecahydro-15H-cyclopenta[a]phenanthren-3-one;17-Hydroxy-19-nor-17a-pregn-5(10)-en-20-yn-3-one; 17a-Ethinyl-17b-hydroxy-D5(10)-estren-3-one; 17a-Ethynyl-17-hydroxy-5(10)-estren-3-one; 17a-Ethynyl-17b-hydroxy-5(10)-estrene-3-one; 17a-Ethynyl-17b-hydroxy-D5(10)-estren-3-one; 17a-Ethynylestr-5(10)-ene-17b-ol-3-one; 17a-Ethynylestra-5(10)-ene-17b-ol-3-one; 17b-Hydroxy-19-nor-17a-pregn-5(10)-en-20-yn-3-one;3-Oxo-17b-hydroxy-17a-ethynyl-5(10)-estrene; Enidrel;NSC 15432; Norethinodrel; Norethynodrel; Noretynodrel; SC 4642
EINECS(EC#)200-682-1
Molecular FormulaC20H26 O2
Molecular Weight298.46
Chemical Properties
refractive index1.577
Safety Data

Hazard T
Risk 45-61
Safety

Suspected carcinogen with experimental tumorigenic data. Human and experimental reproductive effects. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes. 
Hazard Codes:
ToxicT
Risk Statements:
R45:May cause cancer. 
R61:May cause harm to the unborn child.
Safety Statements:
S53:Avoid exposure - obtain special instructions before use. 
S22:Do not breathe dust. 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
WGK Germany: 3
RTECS: RC8980000


Toxicity
1.    

dni-hmn:lyms 50 µmol/L

    PSEBAA    Proceedings of the Society for Experimental Biology and Medicine. 146 (1974),401.
2.    

dns-rat:lvr 100 µmol/L

    CRNGDP    Carcinogenesis. 6 (1985),1201.
3.    

oth-mus-par 16 µg/kg

    AJOGAH    American Journal of Obstetrics and Gynecology. 120 (1974),390.
4.    

cyt-mus:oth 10 mg/L

    AJOGAH    American Journal of Obstetrics and Gynecology. 120 (1974),390.

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