68-26-8|RetinolProducts Supply - Chemical intermediates Network

Retinol cas no:68-26-8

Synonyms: Retinol,all-trans- (8CI);2,4,6,8-Nonatetraen-1-ol, 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-,(all-E)-;A-Mulsal;A-Vi-Pel;Acon;Agiolan;Alcovit A;Alphalin;Anatola;Anti-Infective vitamin;Aoral;Apostavit;Aquasol A Parenteral;Avibon;Avitol;Axerophthol;Biosterol;Disatabs Tabs;Dofsol;Epiteliol;Lard Factor;NSC 122759;Oleovitamin a;Ophthalamin;PlivitA;Retinol 50C;Tegosphere VitA;Thalasphere;Veroftal;Vi-Dom-A;Vitamin Aalcohol, all-trans-;Vitamin A1 alcohol;Vitamin A1, all-trans-;Vitpex;all-trans-Retinol;all-trans-Vitamin A;all-trans-Vitamin A alcohol;trans-VitaminA alcohol;

Identification

NameRetinol
CAS68-26-8
SynonymsRetinol,all-trans- (8CI);2,4,6,8-Nonatetraen-1-ol, 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-,(all-E)-;A-Mulsal;A-Vi-Pel;Acon;Agiolan;Alcovit A;Alphalin;Anatola;Anti-Infective vitamin;Aoral;Apostavit;Aquasol A Parenteral;Avibon;Avitol;Axerophthol;Biosterol;Disatabs Tabs;Dofsol;Epiteliol;Lard Factor;NSC 122759;Oleovitamin a;Ophthalamin;PlivitA;Retinol 50C;Tegosphere VitA;Thalasphere;Veroftal;Vi-Dom-A;Vitamin Aalcohol, all-trans-;Vitamin A1 alcohol;Vitamin A1, all-trans-;Vitpex;all-trans-Retinol;all-trans-Vitamin A;all-trans-Vitamin A alcohol;trans-VitaminA alcohol;
EINECS(EC#)200-683-7
Molecular FormulaC₂₀H₃₀O
Molecular Weight286.452

Chemical Properties

Appearanceyellow to orange crystalline solid
refractive index1.641
storage temp2-8°C

Safety Data

Hazard Xn: Harmful;F: Flammable;N: Dangerous for the environment;
Risk R22;R38
Safety

Moderately toxic by ingestion. Human teratogenic effects by ingestion: developmental abnormalities of the craniofacial area and urogenital system. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Codes:?XnNF
Risk Statements: 22-38-67-65-62-51/53-48/20-11?
R22: Harmful if swallowed
R38: Irritating to skin
R67: Vapours may cause drowsiness and dizziness
R65: Harmful: may cause lung damage if swallowed
R62: Risk of impaired fertility
R51/53: Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
R48/20: Harmful: danger of serious damage to health by prolonged exposure through inhalation
R11: Highly flammable
Safety Statements: 36/37-61-62?
S36/37: Wear suitable protective clothing and gloves
S61: Avoid release to the environment. Refer to special instructions / safety data sheets
S62: If swallowed, do not induce vomitting; seek medical advice immediately and show this container or label
RIDADR: UN 1208 3/PG 2
WGK Germany: 3
RTECS: VH6750000
F: 8-10-16-23?
F 8: Photosensitive
F 10: Keep under argon
F 16: Decomposes easily
F 23: Sensitive to air

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
child	TDLo	oral	912ku/kg/2Y-I (912000iu/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE LIVER: OTHER CHANGES SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	New England Journal of Medicine. Vol. 294, Pg. 805, 1976.
child	TDLo	oral	5475ku/kg/1Y- (5475000iu/kg)	LUNGS, THORAX, OR RESPIRATION: PLEURAL EFFUSION GASTROINTESTINAL: OTHER CHANGES MUSCULOSKELETAL: OTHER CHANGES	Clinical Pediatrics Vol. 21, Pg. 435, 1982.
infant	LDLo	oral	442ku/kg/11D- (442000iu/kg)	BEHAVIORAL: ANOREXIA (HUMAN BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"	Archives of Pathology and Laboratory Medicine. Vol. 108, Pg. 838, 1984.
man	TDLo	oral	1217ku/kg/1Y- (1217000iu/kg)	LIVER: "HEPATITIS, FIBROUS (CIRRHOSIS, POST-NECROTIC SCARRING)" BLOOD: HEMORRHAGE BLOOD: CHANGES IN SPLEEN	Liver Annual. Vol. 12, Pg. 381, 1992.
mouse	LD50	intraperitoneal	1510mg/kg (1510mg/kg)	?	Journal of the American Academy of Dermatology. Vol. 6, Pg. 652, 1982.
mouse	LD50	oral	1510mg/kg (1510mg/kg)	?	"The Retinoids, Vol.2," Sporn, M.B., et al., eds., New York, Academic Press, Inc., 1984Vol. 2, Pg. 287, 1984.
rat	LD50	oral	2gm/kg (2000mg/kg)	?	Acta Dermato-Venereologica, Supplementum. Vol. 74, Pg. 29, 1975.
women	TDLo	oral	91000iu/kg/26 (91000iu/kg)	BEHAVIORAL: ANOREXIA (HUMAN LIVER: "JAUNDICE, OTHER OR UNCLASSIFIED" SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	American Journal of Medicine. Vol. 97, Pg. 523, 1994.

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Retinol cas no:68-26-8

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