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Ethanol,2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]- cas no:68-88-2

Synonyms: Ethanol,2-[2-[4-(4-chloro-a-phenylbenzyl)-1-piperazinyl]ethoxy]- (6CI); Ethanol, 2-[2-[4-(p-chloro-a-phenylbenzyl)-1-piperazinyl]ethoxy]-(8CI); (?à)-Hydroxyzine; 1-(p-Chloro-a-phenylbenzyl)-4-[2-((2-hydroxyethoxy)ethyl)]piperazine;1-(p-Chlorobenzhydryl)-4-[2-(2-hydroxyethoxy)ethyl]diethylenediamine;1-(p-Chlorobenzhydryl)-4-[2-(2-hydroxyethoxy)ethyl]piperazine;1-(p-Chlorodiphenylmethyl)-4-[2-(2-hydroxyethoxy)ethyl]piperazine;2-[2-[4-(p-Chloro-a-phenylbenzyl)-1-piperazinyl]ethoxy]ethanol; Hydroxizine; Hydroxyzin;Hydroxyzine; Hydroxyzyne; NSC 169188; Tran-Q; Tranquizine; U.C.B 4492

Identification
NameEthanol,2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-
CAS68-88-2
SynonymsEthanol,2-[2-[4-(4-chloro-a-phenylbenzyl)-1-piperazinyl]ethoxy]- (6CI); Ethanol, 2-[2-[4-(p-chloro-a-phenylbenzyl)-1-piperazinyl]ethoxy]-(8CI); (?à)-Hydroxyzine; 1-(p-Chloro-a-phenylbenzyl)-4-[2-((2-hydroxyethoxy)ethyl)]piperazine;1-(p-Chlorobenzhydryl)-4-[2-(2-hydroxyethoxy)ethyl]diethylenediamine;1-(p-Chlorobenzhydryl)-4-[2-(2-hydroxyethoxy)ethyl]piperazine;1-(p-Chlorodiphenylmethyl)-4-[2-(2-hydroxyethoxy)ethyl]piperazine;2-[2-[4-(p-Chloro-a-phenylbenzyl)-1-piperazinyl]ethoxy]ethanol; Hydroxizine; Hydroxyzin;Hydroxyzine; Hydroxyzyne; NSC 169188; Tran-Q; Tranquizine; U.C.B 4492
EINECS(EC#)200-693-1
Molecular FormulaC21H27 Cl N2 O2
Molecular Weight374.95
Chemical Properties
storage tempKeep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Safety Data

Safety

Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. Experimental teratogenic and reproductive effects. When heated to decomposition it emits very toxic fumes of Cl and NOx.
Attentions:
1. Storage: Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
2. Handling: All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
 


Toxicity
1.    

orl-rat LD50:840 mg/kg

    CHTPBA    Chimica Therapeutica. 3 (1968),210.
2.    

ipr-rat LD50:160 mg/kg

    CHTPBA    Chimica Therapeutica. 3 (1968),210.
3.    

ivn-rat LD50:45 mg/kg

    ANPBAZ    Acta Neurologia et Psychiatrica Belgica. 61 (1961),669.
4.    

orl-mus LD50:480 mg/kg AANEAB 7,87,63

5.    

ipr-mus LD50:81,300 µg/kg

    DPHFAK    Dissertationes Pharmaceuticae et Pharmacologicae. 23 (1971),281.
6.    

ivn-mus LD50:137 mg/kg

    27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,237.

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Yann Pharmachem Co., Ltd.
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Boc Sciences
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