68-89-3|Aminopyrine sodium sulfonateProducts Supply

Aminopyrine sodium sulfonate cas no:68-89-3

Synonyms: Dipyrone(6CI);Methanesulfonic acid, (antipyrinylmethylamino)-, sodium salt (8CI);ARPF;Optalgin;Pyralgine;Pyretin;Sodium1-phenyl-2,3-dimethyl-5-pyrazolone-4-methylaminomethanesulfonate;Sodium noramidopyrine methanesulfonate;Sulpin;Sulpyrine;Algopyrin;Anador;Analgin;Andolor;Conmel;Diprofarn;Metamizol;Metamizole sodium;Metamizole sodium salt;Methamizole sodium;Metilon;Neo-melubrine;Noramidopyrine methanesulfonatesodium;Noraminophenazone sodium mesylate;Novalgetol;Novamidazophen;Novaminsulfone;Novaminsulfonium;Noveltex;

Identification

NameAminopyrine sodium sulfonate
CAS68-89-3
SynonymsDipyrone(6CI);Methanesulfonic acid, (antipyrinylmethylamino)-, sodium salt (8CI);ARPF;Optalgin;Pyralgine;Pyretin;Sodium1-phenyl-2,3-dimethyl-5-pyrazolone-4-methylaminomethanesulfonate;Sodium noramidopyrine methanesulfonate;Sulpin;Sulpyrine;Algopyrin;Anador;Analgin;Andolor;Conmel;Diprofarn;Metamizol;Metamizole sodium;Metamizole sodium salt;Methamizole sodium;Metilon;Neo-melubrine;Noramidopyrine methanesulfonatesodium;Noraminophenazone sodium mesylate;Novalgetol;Novamidazophen;Novaminsulfone;Novaminsulfonium;Noveltex;
EINECS(EC#)200-694-7
Molecular FormulaC₁₃H₁₆N₃NaO₄S
Molecular Weight333.33861

Chemical Properties

AppearanceWhite or yellowish crystalline powder, odorless, tiny bitter
storage temp2-8°C

Safety Data

Hazard Xn: Harmful;
Risk R42/43
Safety

Hazard Codes?of Aminopyrine sodium sulfonate (CAS NO.68-89-3):? Harmful Xn
Risk Statements: 42/43?
R42/43: May cause sensitization by inhalation and skin contact.
Safety Statements: 36?
S36: Wear suitable protective clothing.
WGK Germany: 2
RTECS: PB1300000
Poison by subcutaneous route. Moderately toxic by several other routes. An experimental teratogen. Other experimental reproductive effects. Human mutation data reported. Questionable carcinogen with experimental neoplastigenic data. See also SULFONATES.?When heated to decomposition it emits very toxic fumes of NO_x, Na₂O, and SO_x.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LDLo	subcutaneous	3gm/kg (3000mg/kg)	?	Arzneimittel-Forschung. Drug Research. Vol. 5, Pg. 213, 1955.
mouse	LC50	inhalation	37200mg/m3 (37200mg/m3)	?	Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 34(10), Pg. 36, 1969.
mouse	LD50	intraperitoneal	250mg/kg (250mg/kg)	?	Archives Internationales de Pharmacodynamie et de Therapie. Vol. 107, Pg. 322, 1956.
mouse	LD50	intravenous	2197mg/kg (2197mg/kg)	?	Arzneimittel-Forschung. Drug Research. Vol. 24, Pg. 600, 1974.
mouse	LD50	oral	2891mg/kg (2891mg/kg)	?	Arzneimittel-Forschung. Drug Research. Vol. 24, Pg. 600, 1974.
mouse	LD50	subcutaneous	69mg/kg (69mg/kg)	?	Russian Pharmacology and Toxicology Vol. 31, Pg. 53, 1968.
mouse	LD50	unreported	2750mg/kg (2750mg/kg)	?	Journal of Drug Research. Vol. 4, Pg. 89, 1972.
rabbit	LD50	oral	2150mg/kg (2150mg/kg)	BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 23(12), Pg. 47, 1979.
rabbit	LDLo	subcutaneous	3gm/kg (3000mg/kg)	?	Arzneimittel-Forschung. Drug Research. Vol. 5, Pg. 213, 1955.
rat	LC	inhalation	> 900mg/m3 (900mg/m3)	?	Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 23(12), Pg. 47, 1979.
rat	LD50	intramuscular	1625mg/kg (1625mg/kg)	?	Russian Pharmacology and Toxicology Vol. 51, Pg. 183, 1988.
rat	LD50	intraperitoneal	2470mg/kg (2470mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Kiso to Rinsho. Clinical Report. Vol. 11, Pg. 478, 1977.
rat	LD50	intravenous	2182mg/kg (2182mg/kg)	?	Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 703, 1976.
rat	LD50	oral	3gm/kg (3000mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Arzneimittel-Forschung. Drug Research. Vol. 21, Pg. 719, 1971.
rat	LD50	subcutaneous	2117mg/kg (2117mg/kg)	?	Arzneimittel-Forschung. Drug Research. Vol. 24, Pg. 600, 1974.

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Aminopyrine sodium sulfonate cas no:68-89-3

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