Escin cas no:6805-41-0
Synonyms: Escigenin,3-(4-O-b-D-glucopyranosyl-2-O-b-D-xylopyranosyl-b-D-glucopyranuronoside),3-hydroxy-2-methylbutyrate, acetate (7CI);3,5-Epoxypicene, escin deriv.;Oleanane, escin deriv.;Aescin;Aescine;Aescusan;Escusan;Eskuzan;Flebostasin Retard;Venocin;b-Escinic acid;
NameEscin
CAS6805-41-0
SynonymsEscigenin,3-(4-O-b-D-glucopyranosyl-2-O-b-D-xylopyranosyl-b-D-glucopyranuronoside),3-hydroxy-2-methylbutyrate, acetate (7CI);3,5-Epoxypicene, escin deriv.;Oleanane, escin deriv.;Aescin;Aescine;Aescusan;Escusan;Eskuzan;Flebostasin Retard;Venocin;b-Escinic acid;
EINECS(EC#)229-880-6
Molecular FormulaC55H86O24
Molecular Weight1131.26
Appearancewhite powder
refractive index1.627
Hazard Xn: Harmful;
Risk R22
Safety
Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Experimental teratogenic effects. When heated to decomposition it emits acrid smoke and irritating fumes. See also α-ESCIN; β-ESCIN; ESCIN, SODIUM SALT; ESCIN TRIETHANOLAMINE SALT.
Hazard Codes: 
Xn
Risk Statements: 22-20/22
R22:Harmful if swallowed.
R20/22:Harmful by inhalation and if swallowed.
Safety Statements: 22-24/25
S22:Do not breathe dust.
S24/25:Avoid contact with skin and eyes.
WGK Germany: 2
RTECS: KF6296000
| 1. |
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orl-rat LD50:833 mg/kg
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KSRNAM Kiso to Rinsho. Clinical Report. 8 (1974),118. |
| 2. |
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ipr-rat LD50:10,150 µg/kg
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KSRNAM Kiso to Rinsho. Clinical Report. 8 (1974),118. |
| 3. |
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scu-rat LD50:150 mg/kg
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KSRNAM Kiso to Rinsho. Clinical Report. 8 (1974),118. |
| 4. |
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ivn-rat LD50:1600 µg/kg
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BCFAAI Bollettino Chimico Farmaceutico. 115 (1976),272. |
| 5. |
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orl-mus LD50:165 mg/kg
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KSRNAM Kiso to Rinsho. Clinical Report. 8 (1974),118. |
| 6. |
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ipr-mus LD50:6700 µg/kg
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NIIRDN Drugs in Japan. Ethical Drugs, 6th Edition 1982 6 (1982),APP-2. |
| 7. |
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scu-mus LD50:38,590 µg/kg
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KSRNAM Kiso to Rinsho. Clinical Report. 8 (1974),118. |
| 8. |
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ivn-mus LD50:2 mg/kg
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BCFAAI Bollettino Chimico Farmaceutico. 115 (1976),272. |
RTECS: KF6296000
