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Eflornithine hydrochloride cas no:68278-23-9

Synonyms: DL-Ornithine,2-(difluoromethyl)-, monohydrochloride;Ornithine, 2-(difluoromethyl)-,monohydrochloride (9CI);NSC 270295;NSC 337250;Vaniqa;

Identification
NameEflornithine hydrochloride
CAS68278-23-9
SynonymsDL-Ornithine,2-(difluoromethyl)-, monohydrochloride;Ornithine, 2-(difluoromethyl)-,monohydrochloride (9CI);NSC 270295;NSC 337250;Vaniqa;
EINECS(EC#)269-532-0
Molecular FormulaC6H13ClF2N2O2
Molecular Weight218.63
Chemical Properties
Appearancewhite solid
Safety Data

Safety

Low toxicity by ingestion and intraperitoneal routes. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and F.
WGK Germany: 3


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal > 3gm/kg (3000mg/kg)   Drugs of the Future. Vol. 6, Pg. 142, 1981.
mouse LD50 oral > 5gm/kg (5000mg/kg)   Drugs of the Future. Vol. 6, Pg. 142, 1981.
rat LD50 intraperitoneal > 3gm/kg (3000mg/kg)   Drugs of the Future. Vol. 6, Pg. 142, 1981.
rat LD50 oral > 5gm/kg (5000mg/kg)   Drugs of the Future. Vol. 6, Pg. 142, 1981.

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UK Green Scientific Co., Limited
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AOPHARM
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