| man |
TDLo |
oral |
209gm/kg/2Y-I (209000mg/kg) |
PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE
BEHAVIORAL: MUSCLE WEAKNESS
CARDIAC: EKG CHANGES NOT DIAGNOSTIC OF ABOVE |
Italian Journal of Neurological Sciences. Vol. 4, Pg. 493, 1983. |
| mouse |
LD50 |
intraperitoneal |
1500mg/kg (1500mg/kg) |
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BLOOD: CHANGES IN SPLEEN |
Oyo Yakuri. Pharmacometrics. Vol. 14, Pg. 535, 1977. |
| mouse |
LD50 |
oral |
> 7500mg/kg (7500mg/kg) |
|
Oyo Yakuri. Pharmacometrics. Vol. 14, Pg. 535, 1977. |
| mouse |
LD50 |
subcutaneous |
4gm/kg (4000mg/kg) |
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BLOOD: CHANGES IN SPLEEN |
Oyo Yakuri. Pharmacometrics. Vol. 14, Pg. 535, 1977. |
| rat |
LD50 |
intraperitoneal |
1420mg/kg (1420mg/kg) |
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
KIDNEY, URETER, AND BLADDER: OTHER CHANGES |
Oyo Yakuri. Pharmacometrics. Vol. 14, Pg. 535, 1977. |
| rat |
LD50 |
oral |
14200mg/kg (14200mg/kg) |
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
KIDNEY, URETER, AND BLADDER: OTHER CHANGES |
Oyo Yakuri. Pharmacometrics. Vol. 14, Pg. 535, 1977. |
| rat |
LD50 |
subcutaneous |
4200mg/kg (4200mg/kg) |
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
KIDNEY, URETER, AND BLADDER: OTHER CHANGES |
Oyo Yakuri. Pharmacometrics. Vol. 14, Pg. 535, 1977. |
