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1-Piperazineethanol,4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]- cas no:69-23-8

Synonyms: 1-Piperazineethanol,4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]- (6CI,7CI,8CI);1-(2-Hydroxyethyl)-4-[3-(trifluoromethyl-10-phenothiazinyl)propyl]piperazine;10-[3-(2-Hydroxyethyl)piperazinopropyl]-2-(trifluoromethyl)phenothiazine;4-[3-(2-Trifluoromethyl-10-phenothiazyl)-propyl]-1-piperazineethanol;4-[3-[2-(Trifluoromethyl)phenothiazin-10-yl]propyl]-1-piperazine ethanol;Elinol; Fluorfenazine; Fluorophenazine; Fluorphenazine; Fluphenazine;Ftorphenazine; Pacinol; Phthorphenazine; S 94; SQ 4918; Siqualine; Siqualon;Triflumethazine; Vespazine

Identification
Name1-Piperazineethanol,4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-
CAS69-23-8
Synonyms1-Piperazineethanol,4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]- (6CI,7CI,8CI);1-(2-Hydroxyethyl)-4-[3-(trifluoromethyl-10-phenothiazinyl)propyl]piperazine;10-[3-(2-Hydroxyethyl)piperazinopropyl]-2-(trifluoromethyl)phenothiazine;4-[3-(2-Trifluoromethyl-10-phenothiazyl)-propyl]-1-piperazineethanol;4-[3-[2-(Trifluoromethyl)phenothiazin-10-yl]propyl]-1-piperazine ethanol;Elinol; Fluorfenazine; Fluorophenazine; Fluorphenazine; Fluphenazine;Ftorphenazine; Pacinol; Phthorphenazine; S 94; SQ 4918; Siqualine; Siqualon;Triflumethazine; Vespazine
EINECS(EC#)200-702-9, 205-674-1, 22
Molecular FormulaC22H26 F3 N3 O S
Molecular Weight437.52
Chemical Properties
Appearancewhite crystalline powder
refractive index1.579
Safety Data

Hazard 6.1 (Packing Group: III) UN NO.
Safety

Poison by ingestion, intraperitoneal, and intravenous routes. Moderately toxic by subcutaneous route. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of F−, NOx, and SOx. See also FLUORIDES.


Toxicity
1.    

orl-rat TDLo:62 mg/kg (9D pre/1-22D preg):REP

    APEPA2    Naunyn-Schmiedebergs Archiv fuer Pharmakologie und Experimentelle Pathologie. 257 (1967),338.
2.    

ipr-rat LD50:100 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 2 (1960),540.
3.    

scu-rat LD50:640 mg/kg

    MDCHAG    Medicinal Chemistry: A Series of Monographs. 4 (2)(1967),199.
4.    

orl-mus LD50:220 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 2 (1960),540.
5.    

ipr-mus LD50:89 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 2 (1960),540.
6.    

ivn-mus LD50:51 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 2 (1960),540.

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