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1-Piperazineethanol,4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]- cas no:69-23-8

Synonyms: 1-Piperazineethanol,4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]- (6CI,7CI,8CI);1-(2-Hydroxyethyl)-4-[3-(trifluoromethyl-10-phenothiazinyl)propyl]piperazine;10-[3-(2-Hydroxyethyl)piperazinopropyl]-2-(trifluoromethyl)phenothiazine;4-[3-(2-Trifluoromethyl-10-phenothiazyl)-propyl]-1-piperazineethanol;4-[3-[2-(Trifluoromethyl)phenothiazin-10-yl]propyl]-1-piperazine ethanol;Elinol; Fluorfenazine; Fluorophenazine; Fluorphenazine; Fluphenazine;Ftorphenazine; Pacinol; Phthorphenazine; S 94; SQ 4918; Siqualine; Siqualon;Triflumethazine; Vespazine

Identification
Name1-Piperazineethanol,4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-
CAS69-23-8
Synonyms1-Piperazineethanol,4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]- (6CI,7CI,8CI);1-(2-Hydroxyethyl)-4-[3-(trifluoromethyl-10-phenothiazinyl)propyl]piperazine;10-[3-(2-Hydroxyethyl)piperazinopropyl]-2-(trifluoromethyl)phenothiazine;4-[3-(2-Trifluoromethyl-10-phenothiazyl)-propyl]-1-piperazineethanol;4-[3-[2-(Trifluoromethyl)phenothiazin-10-yl]propyl]-1-piperazine ethanol;Elinol; Fluorfenazine; Fluorophenazine; Fluorphenazine; Fluphenazine;Ftorphenazine; Pacinol; Phthorphenazine; S 94; SQ 4918; Siqualine; Siqualon;Triflumethazine; Vespazine
EINECS(EC#)200-702-9, 205-674-1, 22
Molecular FormulaC22H26 F3 N3 O S
Molecular Weight437.52
Chemical Properties
Appearancewhite crystalline powder
refractive index1.579
Safety Data

Hazard 6.1 (Packing Group: III) UN NO.
Safety

Poison by ingestion, intraperitoneal, and intravenous routes. Moderately toxic by subcutaneous route. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of F, NOx, and SOx. See also FLUORIDES.


Toxicity
1.    

orl-rat TDLo:62 mg/kg (9D pre/1-22D preg):REP

    APEPA2    Naunyn-Schmiedebergs Archiv fuer Pharmakologie und Experimentelle Pathologie. 257 (1967),338.
2.    

ipr-rat LD50:100 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 2 (1960),540.
3.    

scu-rat LD50:640 mg/kg

    MDCHAG    Medicinal Chemistry: A Series of Monographs. 4 (2)(1967),199.
4.    

orl-mus LD50:220 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 2 (1960),540.
5.    

ipr-mus LD50:89 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 2 (1960),540.
6.    

ivn-mus LD50:51 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 2 (1960),540.

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