69-53-4|AmpicillinProducts Supply - Chemical intermediates Network

Ampicillin cas no:69-53-4

Synonyms: (2S,5R,6R)-6-[(R)-2-Amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; 4-Thia-1-azabicyclo[3.2.0] heptane-2-carboxylic acid, 6-[(aminophenylacetyl)amino]-3,3-dimethyl-7-oxo-, [2S-[2alpha, 5alpha, 6beta(S*)]]-; 6-[(Aminophenylacetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0] heptane-2-carboxylic acid; 6-[D(-)-alpha-aminophenylacetamido]penicillanic acid; Adobacillin; Alpen; Amblosin; Amfipen; amino]-3,3,-dimethyl-7-oxo-4-thia-1-azabicyclo; Aminobenzylpenicillin; Amipenix; Amipenix S; Ampi-Bol; Ampicillin; Ampicillin A; Ampicillin Sulbactam; Ampicin; Ampicina; Ampicyn; Ampilar; Ampimed; Ampipenin; Ampi-Tablinen; Amplisom; Amplital; Ampy-Penyl; Austrapen; Binotal; Bonapicillin; Britacil; Copharcilin; D(-)-alpha-aminobenzylpenicillin; D(-)-aplha-aminobenzylpenicillin; Doktacillin; Grampenil; Guicitrina; Marisilan; Nuvapen; Omnipen; Pen-Bristol; Penbritin; Penbrock; Penicline; Penstabil; Pentrex; Pentrexyl; Polycillin; Ponecil; QI Damp; Rosampline; Synpenin; Tokiocillin; Totacillin; Totalciclina; Totapen; Ultrabion; Unasyn; Viccillin; Wymox;

Identification

NameAmpicillin
CAS69-53-4
Synonyms(2S,5R,6R)-6-[(R)-2-Amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; 4-Thia-1-azabicyclo[3.2.0] heptane-2-carboxylic acid, 6-[(aminophenylacetyl)amino]-3,3-dimethyl-7-oxo-, [2S-[2alpha, 5alpha, 6beta(S*)]]-; 6-[(Aminophenylacetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0] heptane-2-carboxylic acid; 6-[D(-)-alpha-aminophenylacetamido]penicillanic acid; Adobacillin; Alpen; Amblosin; Amfipen; amino]-3,3,-dimethyl-7-oxo-4-thia-1-azabicyclo; Aminobenzylpenicillin; Amipenix; Amipenix S; Ampi-Bol; Ampicillin; Ampicillin A; Ampicillin Sulbactam; Ampicin; Ampicina; Ampicyn; Ampilar; Ampimed; Ampipenin; Ampi-Tablinen; Amplisom; Amplital; Ampy-Penyl; Austrapen; Binotal; Bonapicillin; Britacil; Copharcilin; D(-)-alpha-aminobenzylpenicillin; D(-)-aplha-aminobenzylpenicillin; Doktacillin; Grampenil; Guicitrina; Marisilan; Nuvapen; Omnipen; Pen-Bristol; Penbritin; Penbrock; Penicline; Penstabil; Pentrex; Pentrexyl; Polycillin; Ponecil; QI Damp; Rosampline; Synpenin; Tokiocillin; Totacillin; Totalciclina; Totapen; Ultrabion; Unasyn; Viccillin; Wymox;
EINECS(EC#)200-709-7
Molecular FormulaC16H19N3O4S
Molecular Weight349.4

Chemical Properties

AppearanceCrystalline Solid
storage temp2-8°C

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass8

Safety Data

Hazard Xn:Harmful
Risk R36/37/38;R42/43
Safety Poison by intracerebral route. Moderately toxic by intraperitoneal route. Human systemic effects by ingestion: fever, agranulocytosis, and other blood effects. An experimental teratogen. Mutation data reported. Questionable carcinogen. When heated to decomposition it emits very toxic fumes of NO_x and SO_x.
Hazard Codes:Xn
Risk Statements: 36/37/38-42/43
S36/37/38:Irritating to eyes, respiratory system and skin.
R42/43:May cause sensitization by inhalation and skin contact.
Safety Statements: 22-26-36/37
S22:Do not breathe dust.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37:Wear suitable protective clothing and gloves.

HS Code 29212900

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LDLo	intravenous	> 100mg/kg (100mg/kg)	?	British Medical Journal. Vol. 2, Pg. 197, 1961.
guinea pig	LD50	unreported	7500ug/kg (7.5mg/kg)	?	Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 42(9), Pg. 10, 1977.
man	TDLo	oral	400mg/kg/4W-I (400mg/kg)	BLOOD: AGRANULOCYTOSIS BLOOD: OTHER CHANGES	Annals of Internal Medicine. Vol. 69, Pg. 91, 1968.
mouse	LD50	intracrebral	380mg/kg (380mg/kg)	BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" BEHAVIORAL: EXCITEMENT MUSCULOSKELETAL: CHANGES IN TEETH AND SUPPORTING STRUCTURES	Chemotherapy Vol. 26, Pg. 196, 1980.
mouse	LD50	intraperitoneal	3250mg/kg (3250mg/kg)	BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Eksperimental'naya i Klinicheskaya Farmakoterapiya. Vol. 9, Pg. 83, 1980.
mouse	LD50	intravenous	4600mg/kg (4600mg/kg)	?	Yakugaku Zasshi. Journal of Pharmacy. Vol. 97, Pg. 987, 1977.
mouse	LD50	oral	> 5gm/kg (5000mg/kg)	?	Drugs in Japan Vol. 6, Pg. 57, 1982.
mouse	LD50	parenteral	> 3gm/kg (3000mg/kg)	?	Drugs in Japan Vol. -, Pg. 114, 1995.
mouse	LD50	unreported	28gm/kg (28000mg/kg)	?	Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 42(9), Pg. 10, 1977.
mouse	LDLo	subcutaneous	> 5gm/kg (5000mg/kg)	?	British Medical Journal. Vol. 2, Pg. 197, 1961.
rat	LD50	intraperitoneal	4500mg/kg (4500mg/kg)	?	Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971.
rat	LD50	intravenous	6200mg/kg (6200mg/kg)	?	Drugs in Japan Vol. -, Pg. 88, 1990.
rat	LD50	parenteral	> 3gm/kg (3000mg/kg)	?	Drugs in Japan Vol. -, Pg. 114, 1995.
rat	LD50	unreported	10gm/kg (10000mg/kg)	?	Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 42(9), Pg. 10, 1977.
rat	LDLo	oral	> 5gm/kg (5000mg/kg)	?	British Medical Journal. Vol. 2, Pg. 197, 1961.
rat	LDLo	subcutaneous	> 5gm/kg (5000mg/kg)	?	British Medical Journal. Vol. 2, Pg. 197, 1961.
women	TDLo	oral	160mg/kg/4D-I (160mg/kg)	BLOOD: AGRANULOCYTOSIS BLOOD: THROMBOCYTOPENIA	Annals of Internal Medicine. Vol. 99, Pg. 573, 1983.

supplier list

Tianjin Harmony Technology Development Co., Ltd.: Tel:; Address: Room 601 of BokeBuilding, 100 Fukang Road, Tianjin, China

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Enpeak Technology Co. Ltd.: Tel:+86 797 2198786; Address: 301 new office building, commercial park, 22 red flag road, Ganzhou, JiangXi, China

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Wisechem International Co., Ltd.: Tel:+86-(411)-8259-4468; Address: Room 1005,Rainbow Building, No.23,Renmin Road,Zhongshan District Dalian 116001,

Wuhan Yipharm Co., Ltd.: Tel:+86-(27)-6568-1202, 6568-1246; Address: A6th Floor,Xingcheng Building, No.176 Fazhan Street, Wuhan, Hubei 430022,

Beijing Seajet Scientific Inc.: Tel:+86-(10)-8859-8795; Address: Flat.15B, Block A., 20 Yuanda Road, Haidian, Beijing 100089,

Ningbo Victory & Prosperity Chemistry CO.,LTD.: Tel:+86-(574)-27666767; Address: 21/F, No.11 Bldg, Xin Tian Di, NO 689, Shi Ji Road, NINGBO 315040,

Sol Pharmaceuticals Ltd.: Tel:+91-(40)-2235542; Address: Saphire Building, 5-9-88/2, Fateh Maidan, Hyderabad, Andhra Pradesh 500 001,

Alembic Limited: Tel:+91-(265)-2280550, 3053333; Address: (Formerly known as Alembic Chemical Works Co. Ltd.,), Alembic Veterinary Division, Alembic Road, Vadodara, Gujarat 390 003,

Ampicillin cas no:69-53-4

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