supplier list
- Shenyang Kanglong Pharmaceutical Co., Ltd.
- Tel:86-24-23269483
- Address: 9F-A, Huaxin International Tower, No.219 Qingnian Street, Shenyang, Liaoning
Safety
Moderately toxic by intraperitoneal, subcutaneous and intramuscular routes. An experimental teratogen. Experimental reproductive effects. Used as a non-hormonal post implantation antifertility agent. When heated to decomposition it emits toxic fumes of NOx.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
hamster | LD50 | subcutaneous | > 2gm/kg (2000mg/kg) | Contraception. Vol. 23, Pg. 163, 1981. | |
mouse | LD50 | intraperitoneal | 650mg/kg (650mg/kg) | "Research Frontiers in Fertility Regulation, Proceedings of an International Workshop, 1980," Zatuchni, G.I., et al., eds., Hagerstown, MD, Harper and Row Medical Dept., 1980Vol. -, Pg. 344, 1980. | |
mouse | LD50 | subcutaneous | 3910mg/kg (3910mg/kg) | Contraception. Vol. 23, Pg. 163, 1981. | |
rat | LD50 | intramuscular | > 2gm/kg (2000mg/kg) | Contraception. Vol. 23, Pg. 163, 1981. | |
rat | LD50 | intraperitoneal | 1180mg/kg (1180mg/kg) | "Research Frontiers in Fertility Regulation, Proceedings of an International Workshop, 1980," Zatuchni, G.I., et al., eds., Hagerstown, MD, Harper and Row Medical Dept., 1980Vol. -, Pg. 344, 1980. | |
rat | LD50 | subcutaneous | 3190mg/kg (3190mg/kg) | Contraception. Vol. 23, Pg. 163, 1981. |
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