69408-81-7|1H-Benz[de]isoquinoline-1,3(2H)-dione,5-amino-2-[2-(dimethylamino)ethyl]-Products Supply

1H-Benz[de]isoquinoline-1,3(2H)-dione,5-amino-2-[2-(dimethylamino)ethyl]- cas no:69408-81-7

Synonyms: 5-Amino-2-[2-(dimethylamino)ethyl]-1H-benz[de]isoquinoline-1,3(2H)-dione;FA 142;M-FA 142;MADE-FA 142;NCI 308847;NSC 308847;Nafidimide;

Identification

Name1H-Benz[de]isoquinoline-1,3(2H)-dione,5-amino-2-[2-(dimethylamino)ethyl]-
CAS69408-81-7
Synonyms5-Amino-2-[2-(dimethylamino)ethyl]-1H-benz[de]isoquinoline-1,3(2H)-dione;FA 142;M-FA 142;MADE-FA 142;NCI 308847;NSC 308847;Nafidimide;
Molecular FormulaC₁₆H₁₇N₃O₂
Molecular Weight283.36

Chemical Properties

refractive index1.681

Safety Data

Hazard A poison.
Safety

A poison by intravenous route. Mutation data reported. When heated to decomposition it emits toxic vapors of NO_x.

Toxicity

1.	dnd-hmn-bmr 10 µmol/L	CNREA8 Cancer Research. 47 (1987),1040.
2.	cyt-hmn-lym 250 µg/	PAACA3 Proceedings of the American Association for Cancer Research. 27 (1986),283.
3.	dnd-mus-leu 50 µmol/L	BCPCA6 Biochemical Pharmacology. 34 (1985),3845.
4.	ivn-rat LD :>35 mg/kg	NTIS** National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) No. PB85-100576 .
5.	ivn-mus LD50:67 mg/kg	NTIS** National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) No. PB85-100576 .
6.	ivn-dog LD :>18,400 µg/kg	NTIS** National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) No. PB85-100576 .
7.	ivn-mus LD90:75.1 mg/kg	USXXAM United States Patent Document. (Commissioner of Patents and Trademarks, Washington, DC 20231) #5183821 .

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1H-Benz[de]isoquinoline-1,3(2H)-dione,5-amino-2-[2-(dimethylamino)ethyl]- cas no:69408-81-7

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