13H-4,6:21,24-Dietheno-8,12-metheno-1H-pyrido[3',2':14,15][1,11]dioxacycloeicosino[2,3,4-ij]isoquinolinium,2,3,13a,14,15,16,25,25a-octahydro-9,19-dihydroxy-18,29-dimethoxy-1,14,14-trimethyl-,chloride, hydrochloride, pentahydrate, (13aR,25aS)- (9CI) cas no:6989-98-6

Name13H-4,6:21,24-Dietheno-8,12-metheno-1H-pyrido[3',2':14,15][1,11]dioxacycloeicosino[2,3,4-ij]isoquinolinium,2,3,13a,14,15,16,25,25a-octahydro-9,19-dihydroxy-18,29-dimethoxy-1,14,14-trimethyl-,chloride, hydrochloride, pentahydrate, (13aR,25aS)- (9CI)
CAS6989-98-6
SynonymsTubocuraranium,7',12'-dihydroxy-6,6'-dimethoxy-2,2',2'-trimethyl-, chloride, hydrochloride,pentahydrate;(+)-Tubocurarine chloride hydrochloride pentahydrate;Tubarinepentahydrate;d-Tubocurarine dichloride pentahydrate;
EINECS(EC#)200-356-9
Molecular FormulaC37H41 N2 O6 . Cl H . Cl . 5 H2 O
Molecular Weight785.84

refractive index193 ° (C=1, H2O)
storage temp2-8°C

Hazard T
Safety

Poison by ingestion, subcutaneous, and intravenous routes. Human toxicity: Large doses and overdoses may cause respiratory paralysis and hypotension. When heated to decomposition it emits very toxic fumes of NO_x and Cl⁻.
Hazard Codes:
T: Toxic
Risk Statements about d-Tubocurarine chloride penta-hydrate (6989-98-6):
R25 Toxic if swallowed.
Safety Statements about d-Tubocurarine chloride penta-hydrate (6989-98-6):
S22 Do not breathe dust.
S45 In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.

1.		orl-mus LD50:150 mg/kg		JPETAB    Journal of Pharmacology and Experimental Therapeutics. 118 (1956),395.
2.		scu-mus LD50:600 µg/kg		JPETAB    Journal of Pharmacology and Experimental Therapeutics. 100 (1950),333.
3.		ivn-mus LD50:130 µg/kg		JPETAB    Journal of Pharmacology and Experimental Therapeutics. 118 (1956),388.
4.		orl-cat LDLo:18 mg/kg		JPETAB    Journal of Pharmacology and Experimental Therapeutics. 118 (1956),395.
5.		ivn-cat LD50:400 µg/kg		JPETAB    Journal of Pharmacology and Experimental Therapeutics. 118 (1956),395.
6.		ivn-rbt LD50:146 µg/kg		JPETAB    Journal of Pharmacology and Experimental Therapeutics. 118 (1956),395.