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Trifluridine cas no:70-00-8

Synonyms: Uridine, 2'-deoxy-5-(trifluoromethyl)-(7CI);2'-Deoxy-5-(trifluoromethyl)uridine;5-(Trifluoromethyl)-2'-deoxyuridine;5-(Trifluoromethyl)deoxyuridine;5-Trifluoromethyl-2'-deoxy-b-uridine;5-Trifluorothymidine;NSC 529182;NSC 75520;Trifluorothymidine;Viroptic;

Identification
NameTrifluridine
CAS70-00-8
SynonymsUridine, 2'-deoxy-5-(trifluoromethyl)-(7CI);2'-Deoxy-5-(trifluoromethyl)uridine;5-(Trifluoromethyl)-2'-deoxyuridine;5-(Trifluoromethyl)deoxyuridine;5-Trifluoromethyl-2'-deoxy-b-uridine;5-Trifluorothymidine;NSC 529182;NSC 75520;Trifluorothymidine;Viroptic;
EINECS(EC#)200-722-8
Molecular FormulaC10H11F3N2O5
Molecular Weight296.2
Chemical Properties
Appearancewhite crystalline powder
refractive index1.534
storage temp−20°C
Safety Data

Hazard Xi:Irritant
Risk R20/21/22;R40
Safety

Hazard Codes:?Xn,Xi
Risk Statements: 20/21/22-40
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.?
R40:Limited evidence of a carcinogenic effect.
Safety Statements: 22-36
S22:Do not breathe dust.?
S36:Wear suitable protective clothing.
WGK Germany: 3
RTECS: XP2087500
Hazard Note: Keep Cold


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
monkey LDLo intravenous 400mg/kg (400mg/kg) ? Government Reports Announcements. Vol. 74(9), Pg. 60, 1974.
mouse LD50 intraperitoneal 1931mg/kg (1931mg/kg) ? National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986,
mouse LD50 intravenous 3381mg/kg (3381mg/kg) ? Progress Report Submitted to the National Cancer Institute by Arthur D. Little, Inc. Vol. -, Pg. 260, 1967.
rat LD50 intravenous 2946mg/kg (2946mg/kg) LIVER: OTHER CHANGES Progress Report Submitted to the National Cancer Institute by Arthur D. Little, Inc. Vol. -, Pg. 260, 1967.

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Zhejiang Esun Chemical Co., Ltd.
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Lianyungang Gabriel Bio-chem Technology Co., Ltd.
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Nowa Pharmaceuticals Co., Ltd.
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Achemo Sientific cooperation
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Beijing Ribio Biotech Co.,Ltd
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Beijing HuameiHuli Biochem Ltd
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hangzhou yongsheng holding co.,ltd
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Address: Xiaoshan,Hangzhou

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