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2-Oxazolidinone,5-[(2-methoxyphenoxy)methyl]- cas no:70-07-5

Synonyms: 2-Oxazolidinone,5-[(o-methoxyphenoxy)methyl]- (6CI,7CI,8CI); (?à)-Mephenoxalone; 5-(o-Methoxyphenoxymethyl)-2-oxazolidinone;5-(o-Methoxyphenoxymethyl)-2-oxazolidone; AHR 233; Control-OM; Dorsiflex;Dorsilon; Ekilan; Lenetran; Lenetran Tab; Lenetranat; Mephenoxalone;Methoxadone; Methoxydon; Methoxydone; Metoxadon; Metoxadone; Moderamin; OM-518;Placidex; Riself; Tranpoise; Trepidone; Valans; Xerene

Identification
Name2-Oxazolidinone,5-[(2-methoxyphenoxy)methyl]-
CAS70-07-5
Synonyms2-Oxazolidinone,5-[(o-methoxyphenoxy)methyl]- (6CI,7CI,8CI); (?à)-Mephenoxalone; 5-(o-Methoxyphenoxymethyl)-2-oxazolidinone;5-(o-Methoxyphenoxymethyl)-2-oxazolidone; AHR 233; Control-OM; Dorsiflex;Dorsilon; Ekilan; Lenetran; Lenetran Tab; Lenetranat; Mephenoxalone;Methoxadone; Methoxydon; Methoxydone; Metoxadon; Metoxadone; Moderamin; OM-518;Placidex; Riself; Tranpoise; Trepidone; Valans; Xerene
EINECS(EC#)200-723-3
Molecular FormulaC11H13 N O4
Molecular Weight223.25
Chemical Properties
refractive index1.52
Safety Data

Safety

Moderately toxic by ingestion and intraperitoneal routes. A tranquilizer. When heated to decomposition it emits toxic fumes of NOx.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 800mg/kg (800mg/kg)   Revista de la Asociacion Medica Argentina. Vol. 74, Pg. 82, 1960.
mouse LD50 oral > 5gm/kg (5000mg/kg)   Proceedings of the European Society for the Study of Drug Toxicity. Vol. 11, Pg. 212, 1970.
rat LD intraperitoneal > 1gm/kg (1000mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 134, Pg. 198, 1961.
rat LD50 oral 3820mg/kg (3820mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Toxicology and Applied Pharmacology. Vol. 6, Pg. 642, 1964.

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