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Glutathione cas no:70-18-8

Synonyms: Glutathione(8CI);Glycine, N-(N-L-g-glutamyl-L-cysteinyl)-;Copren;Glutathion;Glutathione-SH;Glutide;Glutinal;Isethion;L-Glutathione;N-(N-L-g-Glutamyl-L-cysteinyl)glycine;Tathione;g-Glutamylcysteinylglycine;g-L-Glutamyl-L-cysteinylglycine;Glycine, L-g-glutamyl-L-cysteinyl-;GSH;

Identification
NameGlutathione
CAS70-18-8
SynonymsGlutathione(8CI);Glycine, N-(N-L-g-glutamyl-L-cysteinyl)-;Copren;Glutathion;Glutathione-SH;Glutide;Glutinal;Isethion;L-Glutathione;N-(N-L-g-Glutamyl-L-cysteinyl)glycine;Tathione;g-Glutamylcysteinylglycine;g-L-Glutamyl-L-cysteinylglycine;Glycine, L-g-glutamyl-L-cysteinyl-;GSH;
EINECS(EC#)200-725-4
Molecular FormulaC10H17N3O6S
Molecular Weight307.32
Chemical Properties
AppearanceWhite Powder
alpha-16.5 ° (C=2, H2O)
refractive index1.571
storage temp2-8°C
Safety Data

Hazard Xi: Irritant;
Risk R68
Safety Moderately toxic by intravenous route. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of SOx and NOx.
Hazard Codes:Xi
Risk Statements: 68-36/37/38
R68: Possible risk of irreversible effects.
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 24/25-36/37/39-27-26
S24/25: Avoid contact with skin and eyes.
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
S27: Take off immediately all contaminated clothing.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany: 2
RTECS: MC0556000
HS Code 29309070

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intramuscular 4gm/kg (4000mg/kg) "Modern Pharmaceuticals of Japan, III," Tokyo, Japan Pharmaceutical, Medical and Dental Suppl Exporters' Assoc., 1968Vol. -, Pg. 97, 1968.
mouse LD50 intraperitoneal 4020mg/kg (4020mg/kg) "Modern Pharmaceuticals of Japan, IV," Tokyo, Japan Pharmaceutical, Medical and Dental Supply Exporters' Assoc., 1972Vol. -, Pg. 93, 1972.
mouse LD50 intravenous 2238mg/kg (2238mg/kg) Japanese Journal of Antibiotics. Vol. 38, Pg. 137, 1985.
mouse LD50 oral 5gm/kg (5000mg/kg) "Modern Pharmaceuticals of Japan, IV," Tokyo, Japan Pharmaceutical, Medical and Dental Supply Exporters' Assoc., 1972Vol. -, Pg. 93, 1972.
mouse LD50 subcutaneous 5gm/kg (5000mg/kg) "Modern Pharmaceuticals of Japan, IV," Tokyo, Japan Pharmaceutical, Medical and Dental Supply Exporters' Assoc., 1972Vol. -, Pg. 93, 1972.
rabbit LD50 intravenous > 2gm/kg (2000mg/kg) Biochemical Journal. Vol. 41, Pg. 325, 1947

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