70052-12-9|EflornithineProducts Supply - Chemical intermediates Network

Eflornithine cas no:70052-12-9

Synonyms: 2-(Difluoromethyl)-DL-ornithine;2-(Difluoromethyl)ornithine;DFMO;DFMO (growth regulator);DL-2-(Difluoromethyl)ornithine;DL-a-(Difluoromethyl)ornithine;Elfornithine;Ornidyl;a,d-Diamino-a-(difluoromethyl)valericacid;a-(Difluoromethyl)-DL-ornithine;a-(Difluoromethyl)ornithine;

Identification

NameEflornithine
CAS70052-12-9
Synonyms2-(Difluoromethyl)-DL-ornithine;2-(Difluoromethyl)ornithine;DFMO;DFMO (growth regulator);DL-2-(Difluoromethyl)ornithine;DL-a-(Difluoromethyl)ornithine;Elfornithine;Ornidyl;a,d-Diamino-a-(difluoromethyl)valericacid;a-(Difluoromethyl)-DL-ornithine;a-(Difluoromethyl)ornithine;
Molecular FormulaC₆H₁₂F₂N₂O₂
Molecular Weight182.20

Safety Data

Safety

Human systemic effects by intravenous route: cardiomyopathy, pulse rate decrease, fall in blood pressure. An experimental teratogen. Other experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of F⁻ and NO_x.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
man	TDLo	intravenous	9084mg/kg/2W- (9084mg/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING BLOOD: THROMBOCYTOPENIA	Drug Intelligence and Clinical Pharmacy. Vol. 21, Pg. 627, 1987.
man	TDLo	oral	800mg/kg/4D-I (800mg/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING BLOOD: THROMBOCYTOPENIA	Drug Intelligence and Clinical Pharmacy. Vol. 21, Pg. 627, 1987.
women	LDLo	intravenous	67mg/kg/40M-C (67mg/kg)	CARDIAC: CARDIOMYOPATHY INCLUDING INFARCTION CARDIAC: PULSE RATE VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION	Annals of Internal Medicine. Vol. 105, Pg. 141, 1986.

supplier list

ZHEJIANG TIME CHEMICAL CO.,LTD.: Tel:+86-576-88068220 13867601722; Address: Sanjia Nongchang,Jiao area,Taizhou City,Zhejiang province,318000 China.

Fast Pharm Co.,Ltd: Tel:8602133538380; Address: No.17#-6D. 830 Lane,Maotai Road Shanghai,SH200336,China

U-Chemo Holding Co.,Limited: Tel:0086-21-61558312; Address: 28C, No.1381, Dong Fang Road, Pudong District, Shanghai, China

Boc Sciences: Tel:1-631-5046093; Address: 45-16 Ramsey Road Shirley, NY 11967, USA

SOGA ENTERPRISES ASIA GROUP: Tel:+86-633-8332928; Address: No.1,Huanghai Yilu.Rizhao,Shandong

Fine Chem Trading LTD: Tel:+44-079-7062-7591; Address: PO Box 292, Greenford, UB6 9ZL, England

Hangzhou Rongda Pharm & Chem Co, Ltd.: Tel:0571-28889928; Address: Xinqiao Development Zone, Yuhang, Hangzhou, China

Nanjing Bangnuo Biotechnology Co., Ltd: Tel:86-1732-7098554; Address: shuanglong road,jiangning, nanjing,jiangsu

Eflornithine cas no:70052-12-9

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