4-Pyrimidinecarboxylicacid, 5-fluoro-1,2,3,6-tetrahydro-2,6-dioxo- cas no:703-95-7
Synonyms: Oroticacid, 5-fluoro- (6CI,8CI);5-Fluoroorotate;ENT 26398;Fluoroorotic acid;NSC 143130;NSC 31712;WR 152520;5-fluoro-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid;4-pyrimidinecarboxylic acid, 5-fluoro-1,2,3,6-tetrahydro-2,6-dioxo-;5-Fluoro orotic acid;5-Fluoro-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid;
Name4-Pyrimidinecarboxylicacid, 5-fluoro-1,2,3,6-tetrahydro-2,6-dioxo-
CAS703-95-7
SynonymsOroticacid, 5-fluoro- (6CI,8CI);5-Fluoroorotate;ENT 26398;Fluoroorotic acid;NSC 143130;NSC 31712;WR 152520;5-fluoro-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid;4-pyrimidinecarboxylic acid, 5-fluoro-1,2,3,6-tetrahydro-2,6-dioxo-;5-Fluoro orotic acid;5-Fluoro-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid;
EINECS(EC#)211-876-0
Molecular FormulaC5H3FN2O4
Molecular Weight174.086723
Appearancewhite to pale
yellow powder
refractive index1.58
storage temp−20°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
HazardclassIRRITANT
Hazard Xn:Harmful;
Risk R22;R36/37/38
Safety
Safety Information of 5-Fluoroorotic acid (CAS NO.703-95-7):
Hazard Codes: 
Xn,
Xi
Risk Statements: 22-36/37/38
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36-36/37/39-27
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
S37:Wear suitable gloves.
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
S27:Take off immediately all contaminated clothing.
WGK Germany: 3
RTECS: UV7800000
F: 10
Hazard Note: Irritant
HazardClass: IRRITANT
Poison by intraperitoneal route. Moderately toxic by ingestion. When heated to decomposition it emits very toxic fumes of F− and NOx.
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
oral |
981mg/kg (981mg/kg) |
|
National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986, |
| rat |
LD50 |
intraperitoneal |
300mg/kg (300mg/kg) |
|
Advances in Teratology. Vol. 3, Pg. 181, 1968. |
