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Benzene cas no:71-43-2

Synonyms: 1,3,5-Cyclohexatriene;Benzol; Benzole; Coal naphtha; Cyclohexatriene; NSC 67315; Phene; Phenylhydride; Pyrobenzol; Pyrobenzole; [6]Annulene

Identification
NameBenzene
CAS71-43-2
Synonyms1,3,5-Cyclohexatriene;Benzol; Benzole; Coal naphtha; Cyclohexatriene; NSC 67315; Phene; Phenylhydride; Pyrobenzol; Pyrobenzole; [6]Annulene
EINECS(EC#)200-753-7
Molecular FormulaC6H6
Molecular Weight78.11
Chemical Properties
AppearanceClear liquid
refractive index1.5011
storage temp0-6°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass3
Safety Data

Hazard F: Flammable;T: Toxic;
Risk R45;R46;R11;R36/38;R48/23/24/25;R65
Safety

Hazard Codes:?FlammableF,ToxicT
Risk Statements: 45-46-11-36/38-48/23/24/25-65-39/23/24/25-23/24/25?
R45:May cause cancer.?
R46:May cause heritable genetic damage.?
R11:Highly flammable.?
R36/38:Irritating to eyes and skin.?
R39:Danger of very serious irreversible effects.??
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.?
R65:Harmful: may cause lung damage if swallowed.?
R48:Danger of serious damage to health by prolonged exposure.
Safety Statements: 53-45-36/37?
S53:Avoid exposure - obtain special instructions before use.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S36/37:Wear suitable protective clothing and gloves.
RIDADR: UN 1114 3/PG 2
WGK Germany: 3
RTECS: CY1400000


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LCLo inhalation 170000mg/m3 (170000mg/m3) ? "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 324, 1955.
dog LCLo inhalation 146000mg/m3 (146000mg/m3) ? "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 324, 1955.
dog LDLo oral 2gm/kg (2000mg/kg) ? "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1313, 1935.
frog LDLo subcutaneous 1400mg/kg (1400mg/kg) ? "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1313, 1935.
guinea pig LD50 skin > 9400uL/kg (9.4mL/kg) ? Toxicology and Applied Pharmacology. Vol. 7, Pg. 559, 1965.
guinea pig LDLo intraperitoneal 527mg/kg (527mg/kg) ? "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 42, 1955.
human LCLo inhalation 65mg/m3/5Y (65mg/m3) BLOOD: OTHER CHANGES Archiv fuer Geschwulstforschung. Vol. 44, Pg. 145, 1974.
human LCLo inhalation 2pph/5M (20000ppm) ? Tabulae Biologicae. Vol. 3, Pg. 231, 1933.
human TCLo inhalation 100ppm (100ppm) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"

GASTROINTESTINAL: NAUSEA OR VOMITING
Industrial Medicine. Vol. 17, Pg. 199, 1948.
mammal (species unspecified) LCLo inhalation 20000ppm/5M (20000ppm) ? Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 138, Pg. 65, 1928.
mammal (species unspecified) LD50 oral 5700mg/kg (5700mg/kg) ? Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 39(4), Pg. 86, 1974.
mammal (species unspecified) LDLo intraperitoneal 1500mg/kg (1500mg/kg) PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)

BEHAVIORAL: IRRITABILITY

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
American Journal of Hygiene. Vol. 7, Pg. 276, 1927.
man LDLo oral 50mg/kg (50mg/kg) ? Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 22, Pg. 883, 1980.
man LDLo unreported 194mg/kg (194mg/kg) ? "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970.
man TCLo inhalation 150ppm/1Y-I (150ppm) BLOOD: OTHER CHANGES Blut. Vol. 28, Pg. 293, 1974.
mouse LC50 inhalation 9980ppm (9980ppm) BEHAVIORAL: GENERAL ANESTHETIC

BEHAVIORAL: MUSCLE WEAKNESS

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Journal of Industrial Hygiene and Toxicology. Vol. 25, Pg. 366, 1943.
mouse LD50 intraperitoneal 340mg/kg (340mg/kg) ? Annals of the New York Academy of Sciences. Vol. 243, Pg. 104, 1975.
mouse LD50 oral 4700mg/kg (4700mg/kg) ? Hygiene and Sanitation Vol. 32(3), Pg. 349, 1967.
mouse LD50 skin 48mg/kg (48mg/kg) ? Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 5, 1974.
rabbit LCLo inhalation 45000ppm/30M (45000ppm) ? Journal of Industrial Hygiene and Toxicology. Vol. 26, Pg. 69, 1944.
rabbit LD50 skin > 9400uL/kg (9.4mL/kg) ? Toxicology and Applied Pharmacology. Vol. 7, Pg. 559, 1965.
rabbit LDLo intravenous 88mg/kg (88mg/kg) PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE

GASTROINTESTINAL: GASTRITIS

SENSE ORGANS AND SPECIAL SENSES: HEMORRHAGE: EYE
Journal of Toxicology and Environmental Health. Vol. (Suppl,
rat LC50 inhalation 10000ppm/7H (10000ppm) ? "Toxicology and Biochemistry of Aromatic Hydrocarbons," Gerarde, H., New York, Elsevier, 1960Vol. -, Pg. 113, 1960.
rat LD50 intraperitoneal 1100ug/kg (1.1mg/kg) ? Acta Physiologica Polonica. Vol. 12, Pg. 173, 1961.
rat LD50 oral 930mg/kg (930mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Toxicology and Applied Pharmacology. Vol. 7, Pg. 767, 1965.

supplier list

Jiangsu Yonghua Fine Chemical Co., Ltd.
Tel:+86-(512)-5254-6988
Address:
ESSO Deutschland GmbH
Tel:+49-(40)-6393-0
Address: Kapstadtring 2, Hamburg 22297,
Shanghai Experiment Reagent Co., Ltd.
Tel:+086-(021)-56553207, 56553837
Address: 10-603, No.555 Luding Road, North Zhongshan Road, Shanghai 200070,
Heniks Incorporation
Tel:+91-(22)-23444511
Address: 404, Sujata Chambers, A. B. Gandhi Marg, Masjid Bunder (W), Mumbai, Maharashtra 400009,
Maruzen Petrochemical Co Ltd.
Tel:+81-(3)-3552 9361
Address: 25-10, Hatchobori 2-chome, Chuo-ku, Tokyo 104-8502,
Mitsubishi Petrochemical Co Ltd.
Tel:+81-(3)-3283 6274
Address: Mitsubishi Bldg., 5-2 Marunouchi 2-chome, Chiyoda-ku, Tokyo 100-005,
Nippon Kasei Chemical Company Limited
Tel:+81-(3)-35066211
Address: Sanshin Bldg.,1-4-1, Yuraku-cho, 1-Chome, Chiyoda-ku, Tokyo,
Nippon Steel Chemical Co. Ltd.
Tel:+81-(3)-52077618
Address: 14-1, Sotokanda 4-Chome, Chiyoda-ku, Tokyo 101-0021,
Noahs Ark Chemicals
Tel:+32-(3)-6100135
Address: Twaalfmaandenstraat 14, B-2000 Antwerp,
Lab Express International Inc.
Tel:+1-(973)-227-1700
Address: 10 Madison Road, Suite A, Fairfield, New Jersey 07004,
Puyang Zhongde Petroleum Resins Co. Ltd.
Tel:+86-(393)-8958588/8999588
Address: NO.249, West Shengli Road, Puyang, Henan 457000,
Hazel Mercantile Limited
Tel:+91-(22)-2282-4444, 4009-8900
Address: 701/712 A, Embassy Centre, Nariman Point, Mumbai, Maharashtra 400 021,
Standard Co Ltd
Tel:+48-(81)-71 00 500
Address: UL. K. Olszewskiego 10, Lublin 20-841,
Diosynth Ltd.
Tel:+44-(1592)-712866
Address: Muiredge Industrial Estate, Buckhaven, Fife KY8 1LJ,
Roan Chemicals
Tel:+27-(11)-6664772
Address: P.O. Box 331, Melrose Arch, Johannesburg 2076,

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