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Medroxyprogesterone 17-acetate cas no:71-58-9

Synonyms: Pregn-4-ene-3,20-dione,17-hydroxy-6a-methyl-, acetate(7CI,8CI);Progesterone, 17-hydroxy-6a-methyl-, acetate (6CI);17a-Acetoxy-6a-methylprogesterone;17a-Hydroxy-6a-methyl-4-pregnene-3,20-dione17-acetate;17a-Hydroxy-6a-methylprogesteroneacetate;6a-Methyl-17-acetoxyprogesterone;6a-Methyl-17a-acetoxy-D4-pregnene-3,20-dione;6a-Methyl-17a-acetoxypregn-4-ene-3,20-dione;Amen;CBP 1011;Clinovir;Colirest;Curretab;Cycrin;DMPA;Depo-Prodasone;Depo-Ralovera;Depo-promone;Depomedroxyprogesterone acetate;Farlutal;Farlutin;Lutoral;Medroprogesterone acetate;

Identification
NameMedroxyprogesterone 17-acetate
CAS71-58-9
SynonymsPregn-4-ene-3,20-dione,17-hydroxy-6a-methyl-, acetate(7CI,8CI);Progesterone, 17-hydroxy-6a-methyl-, acetate (6CI);17a-Acetoxy-6a-methylprogesterone;17a-Hydroxy-6a-methyl-4-pregnene-3,20-dione17-acetate;17a-Hydroxy-6a-methylprogesteroneacetate;6a-Methyl-17-acetoxyprogesterone;6a-Methyl-17a-acetoxy-D4-pregnene-3,20-dione;6a-Methyl-17a-acetoxypregn-4-ene-3,20-dione;Amen;CBP 1011;Clinovir;Colirest;Curretab;Cycrin;DMPA;Depo-Prodasone;Depo-Ralovera;Depo-promone;Depomedroxyprogesterone acetate;Farlutal;Farlutin;Lutoral;Medroprogesterone acetate;
EINECS(EC#)200-757-9
Molecular FormulaC24H34O4
Molecular Weight386.53
Chemical Properties
Appearancewhite powder
refractive index1.536
storage tempRefrigerator
Safety Data

Hazard Xn:Harmful
Risk R40;R48
Safety

Hazard Codes: Xn
Risk Statements: 40-48 
R40: Limited evidence of a carcinogenic effect
R48: Danger of serious damage to health by prolonged exposur
Safety Statements: 22-36/37/39-45 
S22: Do not breathe dust
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection

S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
WGK Germany: 3
RTECS: TU5010000


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 oral > 5gm/kg (5000mg/kg)   Drugs in Japan Vol. -, Pg. 1196, 1990.
mouse LD50 intraperitoneal > 1500mg/kg (1500mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 18, Pg. 6135, 1984.
mouse LD50 oral > 16gm/kg (16000mg/kg) ENDOCRINE: ADRENAL CORTEX HYPOPLASIA Kiso to Rinsho. Clinical Report. Vol. 18, Pg. 6135, 1984.
mouse LD50 subcutaneous > 1500mg/kg (1500mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 18, Pg. 6135, 1984.
rat LD50 intraperitoneal > 900mg/kg (900mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 18, Pg. 6135, 1984.
rat LD50 oral > 6400mg/kg (6400mg/kg) LIVER: OTHER CHANGES Kiso to Rinsho. Clinical Report. Vol. 18, Pg. 6135, 1984.
rat LD50 subcutaneous > 900mg/kg (900mg/kg)   Kiso to Rinsho. Clinical Report. Vol. 18, Pg. 6135, 1984.
women TDLo intravenous 10mg/kg (10mg/kg) SENSE ORGANS AND SPECIAL SENSES: INCREASED INTRAOCULAR PRESSURE: EYE Advances in Planned Parenthood. Vol. 8, Pg. 103, 1972.
women TDLo intravenous 21mg/kg (21mg/kg) SENSE ORGANS AND SPECIAL SENSES: INCREASED INTRAOCULAR PRESSURE: EYE Advances in Planned Parenthood. Vol. 8, Pg. 103, 1972.

supplier list

Arrow Chemical Inc
Tel:+1-201-6644100
Address: 223 Old Rock Road P.O. Box 580 07675 Westwood, NJ
Hubei XinRunde Chemical Co., Ltd
Tel:86-27-83214668
Address: East and West Lake District, Wuhan, China
Hubei XinRunde Chemical Co., Ltd
Tel:86-27-83214668
Address: East and West Lake District, Wuhan, China
Nanjing Bangnuo Biotechnology Co., Ltd
Tel:86-1732-7098554
Address: shuanglong road,jiangning, nanjing,jiangsu
Hubei XinRunde Chemical Co., Ltd
Tel:86-27-83214668
Address: East and West Lake District, Wuhan, China
Wuhan H.X.K Fine Chemicals Co.,LTD
Tel:86-27-59721024
Address: No. 139, hanyang Road, hubei city, Hubei Prov. China 434000
Hubei XinRunde Chemical Co., Ltd
Tel:86-27-83214668
Address: East and West Lake District, Wuhan, China
Hebei yanxi chemical co., LTD
Tel:86-311-66561638
Address: Zhang zhe, guangzong county, xingtai city, hebei p
Wuhan Dahua Weiye Pharmaceutical Co.,Ltd
Tel:86-27-59335372
Address: daijiashan 45,jiangan economic departmen zone,wuhan,hubei,China
Wuhan Dahua Weiye Pharmaceutical Co.,Ltd
Tel:86-27-59335372
Address: daijiashan 45,jiangan economic departmen zone,wuhan,hubei,China
Wuhan Senwayer Century chemical Co.,Ltd
Tel:86-27-59009407
Address: 20#Xudong Street,Wuhan China
Hubei Yuancheng Saichuang Technology Co., Ltd
Tel:86-27-68886732
Address: 28# Golden Avenue, Golden Industrial Zone, Zhengdian Street, Jiangxia District, Wuhan City, Hubei, P. R. China
Hubei Yuancheng Saichuang Technology Co., Ltd
Tel:86-27-68886732
Address: 28# Golden Avenue, Golden Industrial Zone, Zhengdian Street, Jiangxia District, Wuhan City, Hubei, P. R. China
Hubei Yuancheng Saichuang Technology Co., Ltd
Tel:86-27-68886732
Address: 28# Golden Avenue, Golden Industrial Zone, Zhengdian Street, Jiangxia District, Wuhan City, Hubei, P. R. China
Hangzhou Dayangchem Co., Ltd.
Tel:86-571-88938639
Address: 9/F Unit 2 ChangdiTorch Building, 259 #WenSan Road

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