Cevane-3,4,12,14,16,17,20-heptol,4,9-epoxy-, 3-(3,4-dimethoxybenzoate), (3b,4a,16b)- cas no:71-62-5

NameCevane-3,4,12,14,16,17,20-heptol,4,9-epoxy-, 3-(3,4-dimethoxybenzoate), (3b,4a,16b)-
CAS71-62-5
SynonymsVeratridine(6CI,7CI,8CI); 2H-4,16a-Epoxybenzo[7,8]fluoreno[2,1-b]quinolizine,cevane-3,4,12,14,16,17,20-heptol deriv.; 3-Veratroylveracevine; NSC 7524;Veracevine, veratrate; Veratrine; Veratrine (amorphous)
EINECS(EC#)200-758-4
Molecular FormulaC36H51 N O11
Molecular Weight673.88

Appearancepowder
refractive index1.663
storage temp−20°C

Hazardclass6.1(a)

Hazard T+: Very toxic;
Risk R26/27/28
Safety

Poison by intraperitoneal, subcutaneous, and intravenous routes. Combustible when exposed to heat or flame. When heated to decomposition it emits toxic fumes of NO_x. See also VERATRINE.
Hazard Codes:
T+: Very toxic
Risk Statements:
R26/27/28: Very toxic by inhalation, in contact with skin and if swallowed. 
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements:
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.  
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 1544 6.1/PG 1
WGK Germany: 2
RTECS: YX5600000
F:
F 10: Keep under argon.
HazardClass: 6.1(a)
PackingGroup: II

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LDLo	intravenous	19mg/kg (19mg/kg)	cardiac: arrhythmias (including changes in conduction)	Journal of Pharmacology and Experimental Therapeutics. Vol. 120, Pg. 412, 1957.
mouse	LD50	intraperitoneal	1350ug/kg (1.35mg/kg)		Proceedings of the Society for Experimental Biology and Medicine. Vol. 76, Pg. 847, 1951.
mouse	LD50	subcutaneous	6300ug/kg (6.3mg/kg)	behavioral: convulsions or effect on seizure threshold lungs, thorax, or respiration: cyanosis behavioral: ataxia	Journal of Pharmacology and Experimental Therapeutics. Vol. 113, Pg. 89, 1955.
rat	LD50	intraperitoneal	3500ug/kg (3.5mg/kg)	lungs, thorax, or respiration: cyanosis lungs, thorax, or respiration: respiratory depression gastrointestinal: changes in structure or function of salivary glands	Journal of Pharmacology and Experimental Therapeutics. Vol. 78, Pg. 238, 1943.