4,6(1H,5H)-Pyrimidinedione,5-ethyldihydro-5-(1-methylbutyl)-2-thioxo-, sodium salt (1:1) cas no:71-73-8
Synonyms: 4,6(1H,5H)-Pyrimidinedione,5-ethyldihydro-5-(1-methylbutyl)-2-thioxo-, monosodium salt (9CI); Barbituricacid, 5-ethyl-5-(1-methylbutyl)-2-thio-, sodium deriv. (7CI); Barbituric acid,5-ethyl-5-(1-methylbutyl)-2-thio-, sodium salt (8CI);5-Ethyl-5-(1-methylbutyl)-2-thiobarbituric acid monosodium; Farmotal; Hypnostan;Intra-Vital Sodium; Intraval sodium; Leopental; Nesdonal; Nesdonal sodium;Penthiobarbital sodium; Pentothal; Pentothal sodium; RS-Thiopental sodium;Ravonal; Sodium 5-ethyl-5-(1-methylbutyl)-2-thiobarbiturate; Sodium 5-ethyl-5-(a-methylbutyl)-2-thiobarbiturate;Sodium penthiobarbital; Sodium pentothal; Sodium pentothiobarbital; Sodiumthiopental; Sodium thiopentobarbital; Sodium thiopentone; Soluble thiopentone;Thiomebumal sodium; Thionembutal; Thionembutal sodium; Thiopental sodium;Thiopental sodium salt; Thiopentobarbitone sodium; Thiopentone sodium; Thiothalsodium; Tiopental sodium; Trapanal; Trapanal sodium
Name4,6(1H,5H)-Pyrimidinedione,5-ethyldihydro-5-(1-methylbutyl)-2-thioxo-, sodium salt (1:1)
CAS71-73-8
Synonyms4,6(1H,5H)-Pyrimidinedione,5-ethyldihydro-5-(1-methylbutyl)-2-thioxo-, monosodium salt (9CI); Barbituricacid, 5-ethyl-5-(1-methylbutyl)-2-thio-, sodium deriv. (7CI); Barbituric acid,5-ethyl-5-(1-methylbutyl)-2-thio-, sodium salt (8CI);5-Ethyl-5-(1-methylbutyl)-2-thiobarbituric acid monosodium; Farmotal; Hypnostan;Intra-Vital Sodium; Intraval sodium; Leopental; Nesdonal; Nesdonal sodium;Penthiobarbital sodium; Pentothal; Pentothal sodium; RS-Thiopental sodium;Ravonal; Sodium 5-ethyl-5-(1-methylbutyl)-2-thiobarbiturate; Sodium 5-ethyl-5-(a-methylbutyl)-2-thiobarbiturate;Sodium penthiobarbital; Sodium pentothal; Sodium pentothiobarbital; Sodiumthiopental; Sodium thiopentobarbital; Sodium thiopentone; Soluble thiopentone;Thiomebumal sodium; Thionembutal; Thionembutal sodium; Thiopental sodium;Thiopental sodium salt; Thiopentobarbitone sodium; Thiopentone sodium; Thiothalsodium; Tiopental sodium; Trapanal; Trapanal sodium
EINECS(EC#)200-763-1
Molecular FormulaC11H18 N2 O2 S . Na
Molecular Weight265.36
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Hazard T: Toxic;
Risk R25
Safety
Poison by ingestion, intraperitoneal, rectal, subcutaneous, and intravenous routes. Human systemic effects by intraarterial route: acute arterial occlusion; by rectal route: respiratory depression, body temperature decrease, general anesthetic. An experimental teratogen. Experimental reproductive effects. An intravenous anesthetic. When heated to decomposition it emits toxic fumes of NOx and Na2O.
Safety Information of Pentothal sodium (71-73-8):
Hazard Codes: T
T: Toxic .gif)
Risk Statements: 25
25: Toxic if swallowed
Safety Statements: 36-45
36: Wear suitable protective clothing
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: CQ6475000
HazardClass: 6.1(b)
PackingGroup: III
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rec-hmn TDLo:45 mg/kg:CVS,PUL AACRAT 46,395,67
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| 2. |
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iat-hmn TDLo:7 mg/kg:CVS
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LANCAO Lancet. 2 (1943),571. |
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orl-rat LD50:117 mg/kg
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JPETAB Journal of Pharmacology and Experimental Therapeutics. 115 (1955),432. |
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ipr-rat LD50:115 mg/kg
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ANESAV Anesthesiology. 8 (1947),589. |
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ivn-rat LD50:43,600 µg/kg
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JPETAB Journal of Pharmacology and Experimental Therapeutics. 116 (1956),317. |
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rec-rat LD50:102 mg/kg AACRAT 46,395,67
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orl-mus LD50:208 mg/kg
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JPETAB Journal of Pharmacology and Experimental Therapeutics. 115 (1955),432. |
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ipr-mus LD50:115 mg/kg
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NIIRDN “Drugs in Japan. Ethical Drugs, 6th Edition 1982“ Edited by Japan Pharmaceutical Information Center. 6 (1982),457. |
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scu-mus LD50:225 mg/kg
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ivn-mus LD50:57 mg/kg
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AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. 105 (1956),221. |
| 11. |
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orl-dog LDLo:150 mg/kg
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J |
