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2-Piperidinemethanol, a,a-diphenyl-, hydrochloride (1:1) cas no:71-78-3

Synonyms: 2-Piperidinemethanol,a,a-diphenyl-, hydrochloride (8CI,9CI); Detaril; Gerodil;Gerodyl; Leptidrol; Luxidin; Meratonic; Meratran; Meratran hydrochloride;Meratrans; Piperadrol hydrochloride; Pipradol hydrochloride; Pipradolehydrochloride; Pipradrol hydrochloride; Pipral; Stimolag Fortis; a,a-Diphenyl-2-piperidinemethanol hydrochloride

Identification
Name2-Piperidinemethanol, a,a-diphenyl-, hydrochloride (1:1)
CAS71-78-3
Synonyms2-Piperidinemethanol,a,a-diphenyl-, hydrochloride (8CI,9CI); Detaril; Gerodil;Gerodyl; Leptidrol; Luxidin; Meratonic; Meratran; Meratran hydrochloride;Meratrans; Piperadrol hydrochloride; Pipradol hydrochloride; Pipradolehydrochloride; Pipradrol hydrochloride; Pipral; Stimolag Fortis; a,a-Diphenyl-2-piperidinemethanol hydrochloride
EINECS(EC#)200-764-7
Molecular FormulaC18H21 N O . Cl H
Molecular Weight303.86
Chemical Properties
storage tempControlled Substance, -20°C Freezer
Safety Data

Safety

Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. When heated to decomposition it emits very toxic fumes of HCl and NOx.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 90mg/kg (90mg/kg)   Drugs in Japan Vol. 6, Pg. 632, 1982.
mouse LD50 intravenous 20mg/kg (20mg/kg)   U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#00031,
mouse LD50 oral 120mg/kg (120mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Journal of Pharmacology and Experimental Therapeutics. Vol. 118, Pg. 153, 1956.
mouse LD50 subcutaneous 147mg/kg (147mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Journal of Pharmacology and Experimental Therapeutics. Vol. 118, Pg. 153, 1956.
rabbit LD50 intravenous 15mg/kg (15mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Journal of Pharmacology and Experimental Therapeutics. Vol. 110, Pg. 180, 1954.
rabbit LD50 oral 180mg/kg (180mg/kg)   Compilation of LD50 Values of New Drugs.
rat LD50 intravenous 30mg/kg (30mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Journal of Pharmacology and Experimental Therapeutics. Vol. 110, Pg. 180, 1954.
rat LD50 oral 180mg/kg (180mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Journal of Pharmacology and Experimental Therapeutics. Vol. 110, Pg. 180, 1954.
rat LD50 subcutaneous 240mg/kg (240mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) Journal of Pharmacology and Experimental Therapeutics. Vol. 110, Pg. 180, 1954.

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