supplier list
- Harlan China
- Tel:+86-512-69363203
- Address: Biobay, SIP China
Safety
Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. When heated to decomposition it emits very toxic fumes of HCl and NOx.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 90mg/kg (90mg/kg) | Drugs in Japan Vol. 6, Pg. 632, 1982. | |
mouse | LD50 | intravenous | 20mg/kg (20mg/kg) | U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#00031, | |
mouse | LD50 | oral | 120mg/kg (120mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Journal of Pharmacology and Experimental Therapeutics. Vol. 118, Pg. 153, 1956. |
mouse | LD50 | subcutaneous | 147mg/kg (147mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Journal of Pharmacology and Experimental Therapeutics. Vol. 118, Pg. 153, 1956. |
rabbit | LD50 | intravenous | 15mg/kg (15mg/kg) | BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES |
Journal of Pharmacology and Experimental Therapeutics. Vol. 110, Pg. 180, 1954. |
rabbit | LD50 | oral | 180mg/kg (180mg/kg) | Compilation of LD50 Values of New Drugs. | |
rat | LD50 | intravenous | 30mg/kg (30mg/kg) | BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES |
Journal of Pharmacology and Experimental Therapeutics. Vol. 110, Pg. 180, 1954. |
rat | LD50 | oral | 180mg/kg (180mg/kg) | BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES |
Journal of Pharmacology and Experimental Therapeutics. Vol. 110, Pg. 180, 1954. |
rat | LD50 | subcutaneous | 240mg/kg (240mg/kg) | BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) | Journal of Pharmacology and Experimental Therapeutics. Vol. 110, Pg. 180, 1954. |
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