71486-22-1|VinorelbineProducts Supply - Chemical intermediates Network

Vinorelbine cas no:71486-22-1

Synonyms: Vinorelbina [Spanish];Aspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-15-((2R,6R,8S)-4-ethyl-1,3,6,7,8,9-hexahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino(4,3-b)indol-8-yl)-3-hydroxy-16-methoxy-1-methyl-, methyl ester, (2beta,3beta,4beta,5alpha,12beta,19alpha)-;Navelbine base;KW 2307 base;C-Norvincaleukoblastine, 3,4-didehydro-4-deoxy-;Aspidospermidine-3-carboxylic acid,4-(acetyloxy)-6,7-didehydro-15-[(2R,- 6R,8S)-4-ethyl-1,3,6,7,8,9-hexahydro-8- (methoxycarbonyl)-2,6-methano-2H-azecino[4,- 3-b]indol-8-yl]-3-hydroxy-16-methoxy-1- methyl-,methyl ester,(2a,3a,4a,5R,12a,19R)-;Vinorelbinum [Latin];Vinorelbine bitartrate;Vinorelbine base;

Identification

NameVinorelbine
CAS71486-22-1
SynonymsVinorelbina [Spanish];Aspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-15-((2R,6R,8S)-4-ethyl-1,3,6,7,8,9-hexahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino(4,3-b)indol-8-yl)-3-hydroxy-16-methoxy-1-methyl-, methyl ester, (2beta,3beta,4beta,5alpha,12beta,19alpha)-;Navelbine base;KW 2307 base;C-Norvincaleukoblastine, 3,4-didehydro-4-deoxy-;Aspidospermidine-3-carboxylic acid,4-(acetyloxy)-6,7-didehydro-15-[(2R,- 6R,8S)-4-ethyl-1,3,6,7,8,9-hexahydro-8- (methoxycarbonyl)-2,6-methano-2H-azecino[4,- 3-b]indol-8-yl]-3-hydroxy-16-methoxy-1- methyl-,methyl ester,(2a,3a,4a,5R,12a,19R)-;Vinorelbinum [Latin];Vinorelbine bitartrate;Vinorelbine base;
Molecular FormulaC₄₅H₅₄N₄O₈
Molecular Weight778.93

Chemical Properties

refractive index1.676

Toxicity

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RD2530000

CHEMICAL NAME :: C'-Norvincaleukoblastine, 3',4'-didehydro-4'-deoxy-

CAS REGISTRY NUMBER :: 71486-22-1

LAST UPDATED :: 199706

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C45-H54-N4-O8

MOLECULAR WEIGHT :: 779.03

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 26 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GTKRDX Gan to Kagaku Ryoho. Cancer and Chemotherapy. (1-8-9 Yaesu, Chuo-ku, Tokyo 103, Japan) V.1- 1974- Volume(issue)/page/year: 10,1050,1983

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Vinorelbine cas no:71486-22-1

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CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

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