|
dog
|
ld50
|
intraperitoneal
|
56700ug/kg (56.7mg/kg)
|
sense organs and special senses: mydriasis (pupillary dilation): eye
behavioral: convulsions or effect on seizure threshold
lungs, thorax, or respiration: dyspnea
|
oyo yakuri. pharmacometrics. vol. 23, pg. 1, 1982.
|
|
dog
|
ld50
|
intravenous
|
14200ug/kg (14.2mg/kg)
|
sense organs and special senses: mydriasis (pupillary dilation): eye
behavioral: convulsions or effect on seizure threshold
lungs, thorax, or respiration: dyspnea
|
oyo yakuri. pharmacometrics. vol. 23, pg. 1, 1982.
|
|
dog
|
ld50
|
oral
|
662mg/kg (662mg/kg)
|
sense organs and special senses: mydriasis (pupillary dilation): eye
behavioral: convulsions or effect on seizure threshold
lungs, thorax, or respiration: dyspnea
|
oyo yakuri. pharmacometrics. vol. 23, pg. 1, 1982.
|
|
dog
|
ld50
|
subcutaneous
|
129mg/kg (129mg/kg)
|
sense organs and special senses: mydriasis (pupillary dilation): eye
lungs, thorax, or respiration: dyspnea
behavioral: convulsions or effect on seizure threshold
|
oyo yakuri. pharmacometrics. vol. 23, pg. 1, 1982.
|
|
mouse
|
ld50
|
intraperitoneal
|
83700ug/kg (83.7mg/kg)
|
sense organs and special senses: mydriasis (pupillary dilation): eye
behavioral: convulsions or effect on seizure threshold
lungs, thorax, or respiration: dyspnea
|
oyo yakuri. pharmacometrics. vol. 23, pg. 1, 1982.
|
|
mouse
|
ld50
|
intravenous
|
10300ug/kg (10.3mg/kg)
|
sense organs and special senses: mydriasis (pupillary dilation): eye
lungs, thorax, or respiration: dyspnea
behavioral: convulsions or effect on seizure threshold
|
oyo yakuri. pharmacometrics. vol. 23, pg. 1, 1982.
|
|
mouse
|
ld50
|
oral
|
578mg/kg (578mg/kg)
|
sense organs and special senses: mydriasis (pupillary dilation): eye
behavioral: convulsions or effect on seizure threshold
lungs, thorax, or respiration: dyspnea
|
oyo yakuri. pharmacometrics. vol. 23, pg. 1, 1982.
|
|
mouse
|
ld50
|
subcutaneous
|
82100ug/kg (82.1mg/kg)
|
sense organs and special senses: mydriasis (pupillary dilation): eye
lungs, thorax, or respiration: dyspnea
behavioral: convulsions or effect on seizure threshold
|
oyo yakuri. pharmacometrics. vol. 23, pg. 1, 1982.
|
|
rat
|
ld50
|
intraperitoneal
|
70500ug/kg (70.5mg/kg)
|
sense organs and special senses: mydriasis (pupillary dilation): eye
behavioral: convulsions or effect on seizure threshold
lungs, thorax, or respiration: dyspnea
|
oyo yakuri. pharmacometrics. vol. 23, pg. 1, 1982.
|
|
rat
|
ld50
|
intravenous
|
11400ug/kg (11.4mg/kg)
|
sense organs and special senses: mydriasis (pupillary dilation): eye
behavioral: convulsions or effect on seizure threshold
lungs, thorax, or respiration: dyspnea
|
oyo yakuri. pharmacometrics. vol. 23, pg. 1, 1982.
|
|
rat
|
ld50
|
oral
|
1177mg/kg (1177mg/kg)
|
sense organs and special senses: mydriasis (pupillary dilation): eye
behavioral: convulsions or effect on seizure threshold
lungs, thorax, or respiration: dyspnea
|
oyo yakuri. pharmacometrics. vol. 23, pg. 1, 1982.
|
|
rat
|
ld50
|
subcutaneous
|
169mg/kg (169mg/kg)
|
sense organs and special senses: mydriasis (pupillary dilation): eye
behavioral: convulsions or effect on seizure threshold
lungs, thorax, or respiration: dyspnea
|
oyo yakuri. pharmacometrics. vol. 23, pg. 1, 1982.
|
